Results 71 to 80 of about 10,287,555 (319)

Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection. [PDF]

, 2015
Twenty specific pathogen free cats were experimentally infected with a virulent cat-passaged type I field strain of FIPV. Eighteen cats succumbed within 2-4 weeks to effusive abdominal FIP, one survived for 6 weeks, and one seroconverted without outward ...
Eckstrand, Chrissy, Leutenegger, Christian, Liu, Hongwei, Murphy, Brian, Pedersen, Niels C   +4 more
core   +2 more sources

Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study

European Archives of Oto-Rhino-Laryngology, 2020
Objective To investigate the occurrence of olfactory and gustatory dysfunctions in patients with laboratory-confirmed COVID-19 infection. Methods Patients with laboratory-confirmed COVID-19 infection were recruited from 12 European hospitals.
J. Lechien, C. Chiesa-Estomba, Daniele R. De Siati, M. Horoi, S. L. Le Bon, Alexandra Rodríguez, D. Dequanter, S. Blecic, Fahd El Afia, L. Distinguin, Younès Chekkoury-Idrissi, S. Hans, I. Delgado, C. Calvo‐Henriquez, P. Lavigne, Chiara Falanga, M. Barillari, G. Cammaroto, M. Khalife, P. Leich, Christel Souchay, Camélia Rossi, F. Journé, Julien W. Hsieh, M. Edjlali, R. Carlier, L. Ris, A. Lovato, C. de Filippis, F. Coppée, N. Fakhry, T. Ayad, S. Saussez   +32 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Differences in Report of Post-COVID Conditions Among Adults Tested for SARS-CoV-2 by Race and Ethnicity: 2022 Porter Novelli SummerStyles Survey, U.S.

AJPM Focus
Introduction: Since March 2020, Hispanic and Black/African American persons have made up a disproportionate number of COVID-19 cases, hospitalizations, and deaths.
Leora R. Feldstein, PhD, MSc, Deja Edwards, MPH, Jennifer R. Cope, MD, MPH, Melissa Briggs Hagen, MD, MPH, Sharon Saydah, PhD, MHS   +4 more
doaj   +1 more source

The great lockdown: was it worth it? CEPS Policy Insights No 2020-11 / May 2020 [PDF]

, 2020
What the IMF calls the ‘great lockdown’ has thrown Europe and the global economy into a deep recession. When putting their countries into lockdown, governments essentially pushed the panic button, mostly in the face of rising fatalities.
Gros, Daniel
core  

Drivers of MERS-CoV transmission: what do we know? [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Bias and negative values of COVID-19 vaccine effectiveness estimates from a test-negative design without controlling for prior SARS-CoV-2 infection

Nature Communications
Test-negative designs (TNDs) are used to assess vaccine effectiveness (VE). Protection from infection-induced immunity may confound the association between case and vaccination status, but collecting reliable infection history can be challenging.
Ryan E. Wiegand, Bruce Fireman, Morgan Najdowski, Mark W. Tenforde, Ruth Link-Gelles, Jill M. Ferdinands   +5 more
doaj   +1 more source

Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the U.S. throughout the Delta to Omicron Waves

Vaccines
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into numerous lineages with unique spike mutations and caused multiple epidemics domestically and globally.
Han Di, Elizabeth A. Pusch, Joyce Jones, Nicholas A. Kovacs, Norman Hassell, Mili Sheth, Kelly Sabrina Lynn, Matthew W. Keller, Malania M. Wilson, Lisa M. Keong, Dan Cui, So Hee Park, Reina Chau, Kristine A. Lacek, Jimma D. Liddell, Marie K. Kirby, Genyan Yang, Monique Johnson, Sharmi Thor, Natosha Zanders, Chenchen Feng, Diya Surie, Jennifer DeCuir, Sandra N. Lester, Lydia Atherton, Heather Hicks, Azaibi Tamin, Jennifer L. Harcourt, Melissa M. Coughlin, Wesley H. Self, Jillian P. Rhoads, Kevin W. Gibbs, David N. Hager, Nathan I. Shapiro, Matthew C. Exline, Adam S. Lauring, Benjamin Rambo-Martin, Clinton R. Paden, Rebecca J. Kondor, Justin S. Lee, John R. Barnes, Natalie J. Thornburg, Bin Zhou, David E. Wentworth, Charles Todd Davis   +44 more
doaj   +1 more source

Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2020
On 5 February 2020, in Yokohama, Japan, a cruise ship hosting 3,711 people underwent a 2-week quarantine after a former passenger was found with COVID-19 post-disembarking.
K. Mizumoto, Katsushi Kagaya, A. Zarebski, G. Chowell   +3 more
semanticscholar   +1 more source