Results 131 to 140 of about 89,490 (232)
More and more coronaviruses [PDF]
The recent SARS epidemic has boosted global interest in the discovery of novel human and animal coronaviruses. The number of coronavirus species with complete genomes available has increased from nine in 2003 to about 30 in 2011, of which nine, including
Woo, PCY
core
Serine Protease Inhibitory Activity of Kampo Medicines: One of the Mechanisms Against Cold Syndrome
Serine protease inhibitory activity is involved in the mechanism of Kampo medicines used for treating common cold symptoms Ryokankyomishingeninto exhibited serine protease inhibitory activity in vitro and in vivo. Ryokankyomishingeninto showed anti‐SARS‐CoV‐2 activity in VeroE6/TMPRSS2 cells. ABSTRACT Aim Serine proteases play a key role in coronavirus
Yukiko Matsuo +8 more
wiley +1 more source
The Molecular Biology of Coronaviruses
This chapter discusses the manipulation of clones of coronavirus and of complementary DNAs (cDNAs) of defective-interfering (DI) RNAs to study coronavirus RNA replication, transcription, recombination, processing and transport of proteins, virion assembly, identification of cell receptors for coronaviruses, and processing of the polymerase.
Lai, Michael M.C., Cavanagh, David
openaire +2 more sources
COVID-19, caused by SARS-CoV-2, has emerged as the most destructive emerging infectious disease of the 21st century. Vaccination is an effective method to combat viral diseases.
Yuting Huang +7 more
doaj +1 more source
The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity
ABSTRACT CD4+ T cells orchestrate adaptive immunity against respiratory viruses through functionally distinct subsets, yet the qualitative differences between vaccine‐ and infection‐induced responses remain incompletely understood. This review summarizes current evidence on how CD4+ T cell subsets shape the magnitude, breadth, and durability of ...
Masato Kubo
wiley +1 more source
Identification and characterization of novel bat coronaviruses in Spain. [PDF]
The zoonotic transmission of bat coronaviruses poses a threat to human health. However, the diversity of bat-borne coronaviruses remains poorly characterized in many geographical areas.
Rafael Sanjuán +24 more
core +2 more sources
Bats are natural reservoirs for many emerging viruses, including coronaviruses that were probably progenitors to human coronaviruses with epidemic and pandemic potential, which highlights the importance of screening studies of bat-derived viruses.
Olesia V. Ohlopkova +15 more
doaj +1 more source
Can a shorter peptide be a better antiviral? Structure‐guided optimization of the amphibian peptide Hs‐1 reveals a minimal α‐helical core that, after terminal modification, displays enhanced stability and submicromolar broad‐spectrum activity against enveloped viruses while maintaining a favorable safety profile. Antimicrobial peptides (AMPs) represent
Carla Zannella +10 more
wiley +1 more source
Bat (Chiroptera) viruses of Russia and neighboring countries
Aim. To analyze the diversity of bat viruses in Russia and neighboring countries. To identify the main vectors of these pathogens and possible ways of introduction into the territory of the Russian Federation.In Russia the RNA sequences of 36 ...
A. V. Zhigalin
doaj +1 more source
Semi-Covariance Coefficient Analysis of Spike Proteins from SARS-CoV-2 and Its Variants Omicron, BA.5, EG.5, and JN.1 for Viral Infectivity, Virulence and Immune Escape [PDF]
Semi-covariance has attracted significant attention in recent years and is increasingly employed to elucidate statistical phenomena exhibiting fluctuations, such as the similarity or difference in charge patterns of spike proteins among coronaviruses. In
Botao Zhu +3 more
core +1 more source

