Results 61 to 70 of about 92,615 (230)

Coupling Exponential Rolling Circle Amplification to Lateral Flow Devices for Point‐of‐Care Detection of Viral RNA

Angewandte Chemie, EarlyView.
A new exponential RCA (E‐RCA) system was developed and coupled to a toehold system for release of a bridging DNA, allowing for lateral flow detection. The E‐RCA method uses a secondary primer (P2) that binds RCA products (RCAP) to generate extended P2 products that can re‐prime a partially self‐complementary circular template, generating a complete ...
Amal Mathai, Monsur Ali, Yingfu Li, John D. Brennan   +3 more
wiley   +2 more sources

Back to the Future: Immune Protection or Enhancement of Future Coronaviruses

Microorganisms
Before the emergence of SARS-CoV-1, MERS-CoV, and most recently, SARS-CoV-2, four other coronaviruses (the alpha coronaviruses NL63 and 229E and the beta coronaviruses OC43 and HKU1) had already been circulating in the human population. These circulating
Merit Bartels, Eric Sala Solé, Lotte M. Sauerschnig, Ger T. Rijkers   +3 more
doaj   +1 more source

Predicting the Outbreak Risks and Inflection Points of COVID‐19 Pandemic with Classic Ecological Theories

Advanced Science, 2020
Predicting the outbreak risks and/or the inflection (turning or tipping) points of COVID‐19 can be rather challenging. Here, it is addressed by modeling and simulation approaches guided by classic ecological theories and by treating the COVID‐19 pandemic
Zhanshan (Sam) Ma
doaj   +1 more source

The Microbiology of Coronaviruses

Journal of the Pakistan Medical Association, 2020
The end of 2019 marked the start of coronavirus disease (COVID-19) pandemic from China, which went on to envelope more than 190 countries and territories across the globe. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), from a group of betacoronaviruses, is responsible for COVID-19.
openaire   +2 more sources

Coronaviruses of the veterinary and socio-economic importance: Classification, pathogenicity, transmission, and evolution of the coronaviruses

, 2021
Most of the coronaviruses are known because they are pathogens of veterinary and economic importance or of social importance. The current knowledge on the origin, diversity, evolution of coronaviruses, as well as treatment and prevention strategies, and ...
Ismail, Mohd Iswadi
core   +1 more source

The Correlations Between Epidemiological and Clinical Characteristics, laboratory tests and CT Scan reports in the diagnosis of cases 2019 novel coronavirus pneumonia. A Diagnostic Accuracy Study

Acta Medica Iranica, 2021
The role of laboratory parameters and the relationship of them with radiology reports, CT scan and clinical outcomes in screening of COVID-19 patients not been definitely established, but this disease presented a major challenge in the field of clinical ...
Bobby Branson, Ramin Tavakoli, Mansoor Khaledi, Javad Fathi, Seyed Mohammad Shafiee, Hamed Afkhami, Shahdokht Rastegar   +6 more
doaj   +1 more source

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Steffen, Imke, Kögl, Manfred, Schwegmann-Wessels, Christel, Pumpor, Ksenia, Müller, Marcel A., Herzog, Petra, Kuri, Thomas, Ditt, Vanessa, Weber, Friedemann, Schwarz, Frank, Pfefferle, Susanne, Schöpf, Julia, Kallies, Stefan, Herrler, Georg, Carbajo-Lozoya, Javier, Zimmer, Ralf, Hilgenfeld, Rolf, Friedel, Caroline C., Dall'Armi, Ekatarina von, Drosten, Christian, Niemeyer, Daniela, Thiel, Volker, Züst, Roland, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Pöhlmann, Stefan, Haas, Juergen G.   +27 more
core   +1 more source

Coronaviruses and gastrointestinal diseases [PDF]

Military Medical Research, 2020
Abstract The effects of coronaviruses on the respiratory system are of great concern, but their effects on the digestive system receive much less attention. Coronaviruses that infect mammals have shown gastrointestinal pathogenicity and caused symptoms such as diarrhea and vomiting.
Xi Luo, Guan-Zhou Zhou, Yan Zhang, Li-Hua Peng, Li-Ping Zou, Yun-Sheng Yang   +5 more
openaire   +3 more sources

Ecology, evolution and spillover of coronaviruses from bats

, 2021
In the past two decades, three coronaviruses with ancestral origins in bats have emerged and caused widespread outbreaks in humans, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Yeo, Yao Yu, Port, Julia R, Dee, Lauren, Jax, Elinor, Buchholz, David W, Ruiz-Aravena, Manuel, Lunn, Tamika, Kessler, Maureen K, McKee, Clifton, Faust, Christina, Gamble, Amandine, Jones, Devin N, Yinda, Claude Kwe, Morris, Aaron, Snedden, Celine E, et al.   +15 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source