Results 81 to 90 of about 92,615 (230)
Advanced Science, EarlyView.Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun +18 more
wiley +1 more source
Advanced Science, EarlyView.Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao +6 more
wiley +1 more source
Bat origin of human coronaviruses [PDF]
, 2015 Bats have been recognized as the natural reservoirs of a large variety of viruses. Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human disease outbreaks in the 21st century, Severe ...
Wang, L.-F +11 more
core +1 more source
, 2021 Koronavirusi su patogeni ljudi, većine domaćih i mnogih divljih životinja. Koronavirusi šišmiša zadobili su posebnu pažnju nakon epidemije SARS-a, kada se spoznalo da su šišmiši izvor i rezervoar ogromne raznolikosti koronavirusa sa zoonotskim ...
Požarić, Fran
core
Animal Research and One Health, EarlyView.Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
The human enteric coronaviruses [PDF]
Postgraduate Medical Journal, 1979 Summary A coronarirus was seen in the faeces from 15 (4·2%) of 355 adults with diarrhoea and from 5 (5·2%) of 96 adults without diarrhoea. Similar particles were seen in the faeces from 5 (2·2%) of 227 children aged 1–14 years with gastroenteritis, but in none of those from 230 infants under one year of age with gastroenteritis.
S K, Clarke, E O, Caul, S I, Egglestone
openaire +2 more sources
Biotechnology and Bioengineering, EarlyView.SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann +11 more
wiley +1 more source
Australian bat coronaviruses [PDF]
, 2014 Coronaviruses were responsible for the global outbreak of severe acute respiratory syndrome (SARS) in 2003 and 2004, and the outbreak of Middle East respiratory syndrome (MERS) in 2012. Bats have since been identified as the natural hosts for a number of
Smith, Craig S.
core +4 more sources
Voltage‐programmed capillary gel electrophoresis enables rapid detection of bovine coronavirus DNA
Bulletin of the Korean Chemical Society, EarlyView.A voltage‐programmed capillary gel electrophoresis method enables approximately 20‐fold faster analysis of bovine coronavirus compared with conventional slab gel electrophoresis. Abstract Bovine coronavirus (BCoV) is a major pathogen that causes enteric and respiratory disease in cattle and considerable economic losses in the livestock industry.
Hyunjin Jung +3 more
wiley +1 more source
Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins
Biotechnology Progress, EarlyView.Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann +6 more
wiley +1 more source