Results 91 to 100 of about 78,570 (186)

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

The Molecular Biology of Coronaviruses

, 1997
This chapter discusses the manipulation of clones of coronavirus and of complementary DNAs (cDNAs) of defective-interfering (DI) RNAs to study coronavirus RNA replication, transcription, recombination, processing and transport of proteins, virion assembly, identification of cell receptors for coronaviruses, and processing of the polymerase.
Lai, Michael M.C., Cavanagh, David
openaire   +2 more sources

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Investigation of the Mechanism and Possibility of Transmission of Coronaviruses through Ventilation and Wastewater Plumbing Systems in Hospitals: A Narrative Review

تحقیقات سلامت در جامعه, 2021
Introduction and purpose: The hospital wastewater plumbing system and ventilation systems can be possible routes of transmission of infectious agents, such as coronaviruses. Therefore, the purpose of this study was to review the conducted studies in this
Yalda Hashempour, Fatemeh Mortezazadeh
doaj  

Structural analysis of the flexibility of the Ubl2 domain within the papain‐like protease of SARS‐CoV‐2

Acta Crystallographica Section F, Volume 82, Issue 6, Page 222-230, June 2026.
The ubiquitin‐like domain 2 (Ubl2) of the SARS‐CoV‐2 virus is necessary for the stability and catalytic efficiency of its papain‐like protease (PLpro). Our crystallographic study reveals that the Ubl2 domain exhibits notable flexibility and can adopt a conformation that places itself away from the PLpro catalytic domain, representing a new conformation
Gian Luca Freiherr von Scholley, Martina Schaefer, Mark D. Tully, Marc-Andre Hograindleur, Montserrat Soler-López, Roman C. Hillig, Christoph Mueller-Dieckmann, Eaazhisai Kandiah   +7 more
wiley   +1 more source

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst, Valérie Sankatsing, Caterina Rizzo, Francesco Baglivo, Elizabeth Button, Marta Carballal Mariño, María Garcés Sánchez, Christine Hagemann, Simon de Lusignan, Oliver Martyn, Marc Raes, Daan Van Brusselen, Joanne Wildenbeest, Sarah Hak, Foekje Stelma, Jojanneke van Summeren, on behalf of the RSV ComNet network   +16 more
wiley   +1 more source

Screening for Active Compounds of Acorus calamus against SARS-CoV-2 Viral Protease and Mechanism Prediction

Pharmaceuticals
COVID-19, caused by SARS-CoV-2, has emerged as the most destructive emerging infectious disease of the 21st century. Vaccination is an effective method to combat viral diseases.
Yuting Huang, Zhaoxing Li, Yuan Ma, Qianqian Wu, Jianping Kong, Lijuan Zhao, Shunxiang Li, Juan Li   +7 more
doaj   +1 more source

Detection and Phylogenetic Analysis of Alphacoronaviruses in Bat Populations of Rostov and Novosibirsk Regions of Russia, 2021–2023

Microbiology Research
Bats are natural reservoirs for many emerging viruses, including coronaviruses that were probably progenitors to human coronaviruses with epidemic and pandemic potential, which highlights the importance of screening studies of bat-derived viruses.
Olesia V. Ohlopkova, Igor V. Popov, Ilia V. Popov, Kristina A. Stolbunova, Marina A. Stepanyuk, Alexey D. Moshkin, Aleksei A. Maslov, Ivan A. Sobolev, Aleksey V. Malinovkin, Elizaveta V. Tkacheva, Daria A. Bogdanova, Ekaterina A. Lukbanova, Alexey M. Ermakov, Alexander Y. Alekseev, Svetoslav D. Todorov, Alexander M. Shestopalov   +15 more
doaj   +1 more source

Bat (Chiroptera) viruses of Russia and neighboring countries

Юг России: экология, развитие
Aim. To analyze the diversity of bat viruses in Russia and neighboring countries. To identify the main vectors of these pathogens and possible ways of introduction into the territory of the Russian Federation.In Russia the RNA sequences of 36 ...
A. V. Zhigalin
doaj   +1 more source

Coronaviruses [PDF]

, 2012
Anderson, Larry J., Schneider, Eileen
openaire   +2 more sources