Results 111 to 120 of about 405,571 (332)

Receptors for Prostaglandins F2α and E2 in Ovine Corpora Lutea during Maternal Recognition of Pregnancy1 [PDF]

open access: bronze, 1992
Gregory J. Wiepz   +4 more
openalex   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol   +17 more
wiley   +1 more source

Getting Gender Right in Video Games, Simplifying for Inclusivity

open access: yesMediAzioni
The video game industry’s meteoric rise since its birth in the 1970s has steadily increased the demand for professional localisers capable of dealing with “game crunch” (Brogan 2022) in what can only be described as “a double-blind process (no ...
Maria Isabel Rivas Ginel, Sarah Theroine
doaj   +1 more source

A comparative study of Bayesian models for unsupervised sentiment detection

open access: yes, 2010
This paper presents a comparative study of three closely related Bayesian models for unsupervised document level sentiment classification, namely, the latent sentiment model (LSM), the joint sentimenttopic (JST) model, and the Reverse-JST model ...
Everson, Richard   +2 more
core   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

open access: yesAdvanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen   +7 more
wiley   +1 more source

A little bit about: analyzing and teaching lexical bundles in academic lectures

open access: yesLanguage Value, 2018
Author/s Elizabeth Neely and Viviana Cortes Georgia State University   ABSTRACT For English as a second language (ESL) or English as a foreign language (EFL) students, high academic listening skills are essential in order to succeed at the ...
lvalue lvalue
doaj  

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

open access: yesAdvanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang   +5 more
wiley   +1 more source

Corpora amylacea are associated with tau burden and cognitive status in Alzheimer’s disease [PDF]

open access: gold, 2022
Connor M. Wander   +11 more
openalex   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

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