Results 121 to 130 of about 2,386,057 (296)

Gewisse Unterschiede ...: Sechs Fragen an Ferdinand Pavel [PDF]

Public R&D, Research fund ...
Corporate author
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Criteria for designing a visual identity guide for university institutions in the light of the marketing thought of university education (an applied study on Helwan University)

Journal of Architecture, Art & Humanistic Science
This research deals with the study of the criteria for designing an institutional visual identity guide for Helwan University, given the important and increasing role that the corporate identity “branding” plays as one of the most prominent means of ...
Dr. Enas Abdel Raouf Sayed okka
doaj   +1 more source

The impact of tournament incentives on corporate credit repair: Evidence from China. [PDF]

PLoS One
Wang J, You Y, Dong Y, Guo R.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Der Mangel an Pflegekräften ist ein europaweites Problem: Acht Fragen an Erika Schulz [PDF]

Ageing populations, Need for long term ...
Corporate author
core  

Commercial determinants of health revisited: integrating business scholarship for greater public health impact. [PDF]

Global Health
Park J, Husted BW.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Die Landesbanken haben auf der internationalen Bühne nichts verloren: Sieben Fragen an Dorothea Schäfer [PDF]

Regulation, Financial ...
Corporate author
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source