Results 91 to 100 of about 846,583 (292)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Initial Luck, Status-Seeking and Snowballs Lead to Corporate Success and Failure [PDF]

open access: yes
Corporate success stories often resemble a snowball. We show how initial luck in hiring talented people, the resulting technological advantage, superior corporate culture, and status-seeking by workers and by consumers can make small initial differences ...
Amihai Glazer   +2 more
core  

Cultures of Compliance [PDF]

open access: yes, 2017
There has been a cultural turn in discussion and debates about the promise of corporate compliance efforts. These efforts are occurring quickly, without great confidence in their efficacy. Thus the interest in culture.
Langevoort, Donald C
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Особенности моделирования структурной организации концептосферы "corporate culture" в англоязычном социуме [PDF]

open access: yes, 2009
Моделирование структуры концептосферы "corporate culture", состоящую из ядра - концепта "corporate culture" и периферии - ряда (семьи) концептов, вычлененных на основе семейного (фамильного ...
Перелыгина, Т. А.
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Sosialisasi dan Dampak Budaya Organisasi

open access: yesJurnal Ilmu Komunikasi, 2013
: Interest in corporate culture rapidly grew among organization and management researchers and practitioners in Indonesia since 1990. They were impressed by the concept of strong corporate culture which according to research reports was closely related ...
André A. Hardjana
doaj   +1 more source

The Relationship between Ethical Culture and Unethical Behavior in Work Groups: Testing the Corporate Ethical Virtues Model [PDF]

open access: yes
The Corporate Ethical Virtues Model, which is a model for measuring the ethical culture of organizations, has not been tested on its predictive validity. This study tests the relationship between this model and observed unethical behavior in work groups.
Kaptein, S.P.
core   +1 more source

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