Results 91 to 100 of about 5,340,800 (384)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Corporate culture and shareholder value in banking industry [PDF]
This paper analyses the casual relationship between corporate culture and shareholder value using a sample of large banks in the French, German, Italian and U.K. banking systems over the 2000 to 2003 period. Firstly, we measure shareholder value using an
Carretta, Alessandro +3 more
core +1 more source
Toxic Corporate Culture: Assessing Organizational Processes of Deviancy
Administrative Sciences, 2018 There is widespread recognition that organizational culture matters in corporations involved in systemic crime and wrongdoing. However, we know far less about how to assess and alter toxic elements within a corporate culture.
B. Rooij, Adam D. Fine
semanticscholar +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
, 2017 There has been a cultural turn in discussion and debates about the promise of corporate compliance efforts. These efforts are occurring quickly, without great confidence in their efficacy. Thus the interest in culture.
Langevoort, Donald C
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Iustinianus Primus Law Review, 2014 In this paper the authors systematically, detach, but do not separate, corporate culture from organizational culture. Further on corporate culture, from a theoretical viewpoint is established as a specific part of organizational culture, which ...
Aleksandar Klimovski, Timco Mucunski
doaj
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Impact of COVID-19 on corporate culture
Entrepreneurship and Sustainability IssuesThe crisis associated with the global COVID-19 pandemic has had an impact on the economies of all countries in the world. The stoppage of production lines, insufficient demand, and layoffs were just some of the negative effects that Slovak enterprises ...
Silvia Lorincová
doaj +1 more source
An analytical study of employee loyalty and corporate culture satisfaction assessment based on sentiment analysis. [PDF]
Front Psychol, 2022 Xie J, Su RLG, Song J.
europepmc +1 more source