Results 71 to 80 of about 65,979 (293)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Does Corporate Culture Matter? An Empirical Study on Japanese Firms [PDF]
Corporate culture does matter. Using Japanese firms' data from 1987-2000, we have shown that the strength of corporate culture significantly affects corporate policies such as employment policy, management structure, and financial structure. We have also
KUBO Katsuyuki +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Impact of COVID-19 on corporate culture
Entrepreneurship and Sustainability IssuesThe crisis associated with the global COVID-19 pandemic has had an impact on the economies of all countries in the world. The stoppage of production lines, insufficient demand, and layoffs were just some of the negative effects that Slovak enterprises ...
Silvia Lorincová
doaj +1 more source
An analytical study of employee loyalty and corporate culture satisfaction assessment based on sentiment analysis. [PDF]
Front Psychol, 2022 Xie J, Su RLG, Song J.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Tourism & Management Studies, 2015 The major objective of this research is to clarify the contents implied in the concept “corporate culture”, to study the level of development of corporate culture and the formation of mission in the tourist companies in Bulgaria, to explore the ...
Milena Kirilova Filipova
doaj
Research on Sustainable Development of Transport Infrastructure Based on Corporate Culture and Low-Carbon Perspective. [PDF]
J Environ Public Health, 2022 Fang W, Ma C, Lei Z.
europepmc +1 more source
THE LINK BETWEEN ORGANIZATIONAL CULTURE AND CORPORATE PERFORMANCE - AN OVERVIEW [PDF]
The object of this paper is to examine organizational culture and organizational performance through an analysis of the existent culture models and the empirical studies conducted to examine the corporate culture and organizational performance link. Even
Corina Gavrea, Liviu Ilies
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source