Results 61 to 70 of about 4,675,991 (286)
Corporate culture as an important factor in the implementation of knowledge management
Forum Scientiae Oeconomia, 2015 Knowledge and knowledge management are now increasingly seen as a critical part of the corporations. The increase development needs of corporate knowledge as well as innovative activities, whilst underlining the need and importance of corporate culture,
Jaroslava Bučková
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2014 In 1987, Huawei was founded in Shenzhen by Ren Zhengfei, at that time, it was just a small private company with registered capital of RMB 21,000. In 2013, Huawei had more than 140,000 employees, 16 R&D centers in 9 countries including US, India, Japan ...
Chen, Lin
core
Impact of COVID-19 on corporate culture
Entrepreneurship and Sustainability IssuesThe crisis associated with the global COVID-19 pandemic has had an impact on the economies of all countries in the world. The stoppage of production lines, insufficient demand, and layoffs were just some of the negative effects that Slovak enterprises ...
Silvia Lorincová
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Does Corporate Culture Matter for Firm Policies? [PDF]
Economic theories suggest that a firm's corporate culture matters for its policy choices. We construct a parent-spinoff firm panel dataset that allows us to identify culture effects in firm policies from behavior that is inherited by a spinoff firm from ...
Cronqvist, Henrik +2 more
core
Using corporate stories to build the corporate brand:an impression management perspective [PDF]
, 2013 Purpose: A recent area of academic interest within corporate branding and reputation is the use of storytelling in order to differentiate the corporate brand, however there is little empirical research exploring the contents of corporate stories, and how
Spear, Sara, Roper, Stuart
core +1 more source
Tourism & Management Studies, 2015 The major objective of this research is to clarify the contents implied in the concept “corporate culture”, to study the level of development of corporate culture and the formation of mission in the tourist companies in Bulgaria, to explore the ...
Milena Kirilova Filipova
doaj