Results 91 to 100 of about 65,979 (293)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Jurnal Manajemen dan Wirausaha, 2013 A strong application of corporate culture drives a company in improving its performance and achieving its targets. With the result that the corporate culture has a role in increasing the welfare of it’s employees.
Riyan Sisiawan Putra
doaj
Intermediary Management and Employee Corporate Culture Identification Mediation and Mediation Effect Verification. [PDF]
Front Psychol, 2021 Liu M, Li J, Xiong T, Liu T, Chen M.
europepmc +1 more source
Culture and Corporate Governance Statement Disclosure [PDF]
This study examines the influence of culture on Corporate Governance Statement disclosure in the annual reports of the major airline companies in Malaysia and Australia. The cultural research of Hofstede (1980) and the accounting value dimensions of Gray
Salleh Hassan, Theo Christopher
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Technology of formation and development of corporate culture of modern higher school
Ученые записки Российской академии предпринимательства, 2021 The paper presents an analysis of the social technologies of formation of corporate culture of higher education institutions. Defines the contentof the corporate culture as a set of several subcultures, the necessity of the algorithmic process of ...
N. G. Mustaeva
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Corporate culture: threat to researchers [PDF]
Nature, 2017 Liu, Gang, Tan, Juan
openaire +1 more source
Corporate Cash Holdings, National Culture, and Multinationality [PDF]
We examine the relations between national cultures, the multinationality of the firm and its holdings of cash. We develop several hypotheses from well known corporate finance theories and theories of the multinational firm, positing that cultural factors
Solomon Tadesse, Andres Ramirez
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source