Results 81 to 90 of about 922,494 (289)

Why Water? [PDF]

open access: yes, 2009
The report focuses on what businesses should do to manage the reputational, regulatory, and operational risks of their water usage. Four solutions are presented, and the scale and intensity of each solution will vary by sector, geography, and customer ...

core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The role of traditional and new international relations actors in addressing climate change

open access: yesEastern Review, 2019
Addressing global climate change brings up a number of priority issues. The fundamental issue is the definition of the participants in this process and the scope of their competencies and areas of responsibility.
Olena Shevchenko
doaj   +1 more source

The Alternative Minimum Tax and the Behavior of Multinational Corporations [PDF]

open access: yes
This paper examines the extent to which U.S.-based multinational corporations are affected by the alternative minimum tax. More than half of all foreign-source income received by corporations in 1990 was earned by corporations subject to the alternative ...
Andrew B. Lyon, Gerald Silverstein
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Ontological approach to the normative dimension of organizations: an application of Documents Acts Ontology

open access: yesCiência da Informação, 2019
Modeling and knowledge representation are indispensable activities for developing information systems in the scope of modern corporations. In order to accomplish these activities, one should analyze a corporation both in terms of its physical structure ...
Maurício Barcellos Almeida   +3 more
doaj  

State's responsibility for business-related human rights violations in the light of the Strasbourg Court's case-law [PDF]

open access: yesPravni Zapisi, 2019
On the one hand, business entities have a huge potential to contribute to economic and social progress and consequently to the advancement of human rights. On the other, violations of human rights connected with business are very common.
Topić Boris
doaj  

Corporate Criminal Liability for Homicide: A Statutory Framework [PDF]

open access: yes, 2011
Since the nineteenth century, judges, legislators, prosecutors, and academics have grappled with how best to accommodate within the criminal law corporations whose conduct causes the death of others.
Harlow, James W.
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

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