Results 51 to 60 of about 133,752 (286)

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer\u27s disease [PDF]

, 2019
Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years.
Ances, Beau M, Benzinger, Tammie L.S., Blazey, Tyler, Cairns, Nigel J, Chen, Charlie, Cruchaga, Carlos, Fagan, Anne M, Gordon, Brian A, Liu, Jingxia, Morris, John C, Shimony, Joshua S, Su, Yi, Sutphen, Courtney L, Wang, Qing, Wang, Yong   +14 more
core   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

The combination of thermal dysregulation and agenesis of corpus callosum: Shapiro′s or/and reverse Shapiro′s syndrome

Annals of Indian Academy of Neurology, 2013
Shapiro syndrome is an extremely rare condition consisting the clinical triad of recurrent hypothermia, hyperhydrosis and agenesis of the corpus callosum. On the other hand, reverse Shapiro′s sydrome is characterized periodic hyperthermia and agenesis of
Yasemin Topcu, Erhan Bayram, Pakize Karaoglu, Uluc Yis, Semra Hiz Kurul   +4 more
doaj   +1 more source

Whole brain and corpus callosum diffusion tensor metrics: How do they correlate with visual and verbal memory performance in chronic traumatic brain injury [PDF]

Journal of Integrative Neuroscience, 2019
This research investigates the chronic effect of moderate to severe traumatic brain injury on brain white matter integrity, as reflected by diffusion tensor imaging metrics, and the assessment of their correlation to neuropsychological response. Thirteen
Charalambos Yiannakkaras, Nikos Konstantinou, Fofi Constantinidou, Eva Pettemeridou, Eleni Eracleous, Savvas S. Papacostas, Ioannis Seimenis
doaj   +1 more source

Microstructural parameter estimation in vivo using diffusion MRI and structured prior information. [PDF]

, 2016
Diffusion MRI has recently been used with detailed models to probe tissue microstructure. Much of this work has been performed ex vivo with powerful scanner hardware, to gain sensitivity to parameters such as axon radius.
Aboitiz, Alexander, Alexander, Andersson, Assaf, Assaf, Barazany, Basser, Callaghan, Clayden, Clayden, Drobnjak, Dyrby, Eddelbuettel, Eddelbuettel, Feinberg, Gelderen, Hall, Huang, Ianuş, Koch, Lawrenz, Le Bihan, Li, McNab, Neuman, Nilsson, Nilsson, Price, R Core Team. R, Reese, Roberts, Setsompop, Shemesh, Shemesh, Siow, Siow, Stanisz, Stejskal, Swain, Szafer, Xu, Zhang, Zhang   +43 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Disorders of speech and language in child with agenesis of the corpus callosum - case study

Journal of Education, Health and Sport, 2018
Introduction: The corpus callosum is the largest structure of the nerve fibers of the brain. Its main function is to coordinate the transfer of information between the right and left hemispheres of the brain.
Aneta Chrut
doaj   +3 more sources

Age at developmental cortical injury differentially Alters corpus callosum volume in the rat [PDF]

, 2007
Background: Freezing lesions to developing rat cortex induced between postnatal day (P) one and three (P1 – 3) lead to malformations similar to human microgyria, and further correspond to reductions in brain weight and cortical volume.
Glenn D Rosen, R Holly Fitch, Steven W Threlkeld   +2 more
core   +2 more sources

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Parametric Regression on the Grassmannian [PDF]

, 2015
We address the problem of fitting parametric curves on the Grassmann manifold for the purpose of intrinsic parametric regression. As customary in the literature, we start from the energy minimization formulation of linear least-squares in Euclidean ...
Hong, Yi, Kwitt, Roland, Niethammer, Marc, Singh, Nikhil, Vasconcelos, Nuno   +4 more
core   +4 more sources