Results 201 to 210 of about 1,303,482 (284)

Comparison Between QT and Corrected QT Interval Assessment by an Apple Watch With the AccurBeat Platform and by a 12‑Lead Electrocardiogram With Manual Annotation: Prospective Observational Study. [PDF]

JMIR Form Res, 2022
Chokshi S, Tologonova G, Calixte R, Yadav V, Razvi N, Lazar J, Kachnowski S.   +6 more
europepmc   +1 more source

Design of a Laccase Bioelectrode Using Multipoint Covalent Immobilization: Behavior Under Different Stress Conditions and Long‐Term Storage

Electroanalysis, Volume 38, Issue 10, October 2026.
Multipoint covalent immobilization of laccase on a modified carbon paper electrode. Robust biointerface with operational stability under chemical, thermal, mechanical, electrical, and storage stress conditions. The practical implementation of enzyme bioelectrodes is limited by the inherent lability of proteins, which require mild conditions to maintain
W. I. García‐García, G. A. Huerta‐Miranda, K. Juárez, M. Miranda‐Hernández   +3 more
wiley   +1 more source

Prolonged corrected QT interval is associated with cardiac sympathetic nervous function overactivity in patients with severe aortic stenosis: assessment by 123I-metaiodobenzylguanidine myocardial scintigraphy. [PDF]

Heart Vessels
Fukuda Y, Nishio Y, Miyazaki H, Okada Y, Ueda H, Takahashi S, Nakano Y.   +6 more
europepmc   +1 more source

Hepatoprotective Effects of Maillard Reaction Products From Perinereis aibuhitensis: Identification and Metabolomic Insights in a Mouse Model of Alcoholic Liver Disease

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract summarizes the hepatoprotective effects of Maillard reaction products derived from Perinereis aibuhitensis (P‐MRPs) in alcohol‐induced liver injury. Male ICR mice were fed a Lieber‐DeCarli alcohol liquid diet (1%–5%, w/v) for 6 weeks with or without P‐MRPs treatment.
Tonglei Qiao, Yuchun Lu, Teng Teng, Zichen Deng, Feng Liu, Chun‐E Liu   +5 more
wiley   +1 more source

Effect of a Supratherapeutic Dose of Omaveloxolone on the Corrected QT Interval in Healthy Participants: A Randomized, Double-Blind, Placebo- and Active-Controlled, Three-Way Crossover Study. [PDF]

Clin Transl Sci
Zahir H, Murai M, Wu L, Valentine M, Hynes SM.   +4 more
europepmc   +1 more source

Concentration‐QTc Analysis Supporting Thorough QT Study Waiver for Forvisirvat: Electrocardiogram Assay Sensitivity Demonstrated via Meal Effect

The Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Concentration‐QTc analysis from Phase 1 studies is increasingly used to evaluate QTc prolongation risk as an alternative to thorough QT (TQT) studies. According to International Conference on Harmonization E14 documents, such analyses should include exposures at twice the highest clinically relevant exposure instead of a positive control to ...
Yushi Kashihara, Yoshiyuki Igawa, Kei Okita, Masaki Sasaki, Takaki Ohara, Masakatsu Kotsuma, Kazutaka Yoshihara   +6 more
wiley   +1 more source

Permanent Cardiac Pacing in Children: A 30‐Year Follow‐Up Retrospective Study in a Single Pediatric Asian Center

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
This 30‐year retrospective study of pediatric permanent pacing found acceptable long‐term device complication rates, with epicardial leads used predominantly. Pacing‐induced cardiomyopathy occurred only in children with congenital heart disease, highlighting the need for individualized pacing strategies in this cohort and long‐term echocardiographic ...
Jiahui Charmaine Chan, Dyan Zhewei Zhang, Koh Zhi Xuan, Sreekanthan Sundararaghavan, Jonathan Tze Liang Choo, Kah Leng Ho, Eric Tien Siang Lim, Ju Le Tan, Nurhafizah Binte Abdul Aziz, Wan Ting Chan, Monika Kotecha, Jan Hau Lee, Teng Hong Tan   +12 more
wiley   +1 more source

Impact of sequential (first- to third-generation) EGFR-TKI treatment on corrected QT interval in NSCLC patients. [PDF]

Front Oncol
Gan T, Chen J, Wang H, Shang C, Xi S, Fan Z, He B, Zhang M, Zhao L.   +8 more
europepmc   +1 more source

Trends and Demographic Disparities Among Adults With Sudden Cardiac Death and Diabetes Mellitus in the United States: A Nationwide Analysis

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
From 1999 to 2020, 51 756 U.S. deaths documented both sudden cardiac death and diabetes mellitus, with population‐level burden rising significantly (APC +0.46%). Disparities were greatest among men, Black populations, rural residents, and Southern states, with a sharp mortality surge in 2020 coinciding with the COVID‐19 pandemic.
Taha Mehmood, Muhammad Abdullah, Masab Ali, Amina Jamil, Muhammad Husnain Ahmad, Muhammad Mujtaba Tariq, Areej Asif, Sunnia Khan, Moeez Ahmad Saeed, Muhammad Hassan, Aasim Ali, Muhammad Umar Shahid, Shahzaib Ihsan, Muhammad Usama Yasin, Usama Siddique   +14 more
wiley   +1 more source

Do Stimulants Promote Arrhythmic Risk: Insights From a Human‐Induced Pluripotent Stem Cell‐Derived Cardiomyocyte Model

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
At clinically relevant plasma concentrations, stimulant medications produced minimal effects on conduction velocity but modulated automaticity and repolarization in a hiPSC‐derived cardiomyocyte (hiPSC‐CM) model. These findings provide a foundation for future investigations of stimulant‐associated cardiac safety and support the utility of hiPSC‐CM ...
Alia Arslanova, Samantha Wong, Sonia Franciosi, Glen F. Tibbits, Maksymilian Prondzynski, Shubhayan Sanatani   +5 more
wiley   +1 more source