Results 261 to 270 of about 55,874 (301)

Psychotropic Drugs Associated With Corrected QT Interval Prolongation

Journal of Clinical Psychopharmacology, 2009
To study whether listed putative corrected QT (QTc)-prolonging psychotropic drugs indeed prolong the QTc interval under everyday circumstances and to evaluate whether this is a class effect or an individual drug effect, we conducted a prospective population-based cohort study.This study was conducted as part of the Rotterdam Study and included 3377 men
van Noord, C, Straus, SM, Sturkenboom, MC, Hofman, A, Aarnoudse, AJ, BAGNARDI, VINCENZO, Kors, JA, Newton Cheh, C, Witteman, JC, Stricker BH   +9 more
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Relationship between serum bepridil concentration and corrected QT interval

Int. Journal of Clinical Pharmacology and Therapeutics, 2021
Bepridil prolongs the QT interval and can induce torsade de pointes. Although increased bepridil concentration may be a primary cause of prolonged QT, the relationship between serum bepridil concentration and prolonged QT remains unclear. We investigated the relationship between serum bepridil concentration and the corrected QT (QTc) interval in ...
Kazuki, Matsui, Yutaro, Mukai, Kota, Sakakura, Kyoichi, Wada, Tsutomu, Nakamura, Atsufumi, Kawabata, Nobue, Terakawa, Naoki, Hayakawa, Kengo, Kusano, Kouichi, Hosomi, Satoshi, Yokoyama, Mitsutaka, Takada   +11 more
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The impact of fever on corrected QT interval

Journal of Electrocardiology, 2017
We were interested in the impact of fever on the QT interval as information on this subject is limited.We performed a retrospective, single centre study over a two year period, ending December 31st, 2013. Participants were identified using an electronic chart review of emergency department records linked to an ECG data base.
Doran, Drew, Adrian, Baranchuk, Wilma, Hopman, Robert J, Brison   +3 more
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Transient Prolonged Corrected QT interval in Lyme Disease

The Journal of Pediatrics, 2006
Lyme disease, caused by the spirochete Borrelia burgdorferi, has known cardiovascular effects typically manifesting in varying degrees of atrioventricular block. Three patients presented with QT interval prolongation associated with Lyme disease, a previously unreported manifestation of Lyme carditis.
Stephen P, Seslar, Charles I, Berul, Thomas R, Burklow, Frank, Cecchin, Mark E, Alexander   +4 more
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Corrected QT Interval (QT)

1989
The QT interval of the electrocardiogram (ECG) is measured from the onset of ventricular activity to the end of the T wave. Because the QT interval varies with heart rate in normal individuals a “corrected” QT interval is sometimes calculated to factor out heart rate-dependent effects to provide a measure that is independent of rate effects.
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QT interval correction assessment in the anesthetized guinea pig

Journal of Pharmacological and Toxicological Methods, 2015
The anesthetized guinea pig (ANES GP) has proven to be an effective small animal model to evaluate cardiac electrophysiologic effects of drug-candidate molecules during lead optimization. While heart rate (HR) corrected QT interval (QTc) is a key variable to determine test article-dependent repolarization effects, ideal correction methods are an area ...
Pierre, Morissette, Hillary K, Regan, Kevin, Fitzgerald, Sylvain, Bernasconi, Pamela, Gerenser, Jeffrey, Travis, Patrick, Fanelli, Frederick, Sannajust, Christopher P, Regan   +8 more
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Bias and Variance Evaluation of QT Interval Correction Methods

Journal of Biopharmaceutical Statistics, 2008
There is an increasing regulatory emphasis on assessing drug-induced QT interval prolongation. Since QT interval is correlated with heart rate (HR), assessment of drug-induced QT interval prolongation should be made at a standardized HR, resulting in the need to correct QT interval (QTc) for HR. This study investigates the statistical properties of QTc
Yibin, Wang, Guohua, Pan, Alfred, Balch
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QT interval correction methods for rhesus monkeys

2023
Different techniques for QT correction in rhesus ...
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The Relation Between QT Interval, QT Dispersion, Corrected QT Interval, Corrected QT Dispersion and Cardiovascular Risk Variables in Normotensive Obese Children

2019
The goal of this search was to find out whether the sensitivity of QT interval, QT dispersion (QTd), corrected QT (QTc) interval and corrected QT dispersion (QTcd) sensitivity in the early diagnosis of ventricular arrhythmia and cardiovascular mortality in normotensive exists or not and to evaluate their relation to the parameters examined in terms of ...
GÜLER, Tuğba, ORAN, Bülent
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How to correct QT interval after cardiac resynchronisation therapy

Journal of Electrocardiology
This study evaluates various formulae used to correct the QT interval in patients with wide QRS complexes to calculate corrected QT (QTc) following Cardiac Resynchronisation Therapy (CRT).We included patients with severe heart failure and left bundle branch block, presenting with a QRS duration of at least 120 milliseconds, who underwent successful CRT
Amin, Esmailian, Colin, Machado, Hui Chen, Han, Jeffrey, Alison, Mohammad, Alasti   +4 more
openaire   +2 more sources