Results 41 to 50 of about 55,874 (301)
Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer. [PDF]
, 2018 The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in ...
Durairaj, Chandrasekar +12 more
core +2 more sources
A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study. [PDF]
, 2017 Background -Drug-induced QT interval prolongation, a risk factor for life-threatening ventricular arrhythmias, is a potential side effect of many marketed and withdrawn medications.
Behr, ER +11 more
core +2 more sources
QTc interval on 24‐hour holter monitor: To trust or not to trust?
Annals of Noninvasive Electrocardiology, 2022 Introduction QT interval represents the ventricular depolarization and repolarization. Its accurate measurement is critical since prolonged QT can lead to sudden cardiac death.
Mhd Khalil Tamr Agha +6 more
doaj +1 more source
QT peak prolongation predicts cardiac death following stroke [PDF]
, 2015 Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak.
Douglas, Denise +7 more
core +1 more source
Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine [PDF]
, 2015 KAE609 represents a new class of potent, fast-acting, schizonticidal antimalarials. This study investigated the safety and pharmacokinetics of KAE609 in combination with the long-acting antimalarial piperaquine (PPQ) in healthy volunteers.
Griffin, Paul +6 more
core +1 more source
Acute effects of coffee on QT interval in healthy subjects [PDF]
, 2011 The coronary endothelial function is recognized to have an important role in the physiology of the diastolic ventricular relaxation, a phase of the heart cycle that influences the electrocardiographic QT interval.
BUSCEMI, Silvio +3 more
core +3 more sources
Journal of Cardiac Arrhythmias, 2020 Introduction: Chagas’ disease lacks elements to predict which carriers will evolve into cardiac form and which will remain in undetermined form. Objective: To evaluate the relationship between electrocardiographic evolution and Tpeak–Tend and QT ...
Abilio Augusto Fragata Filho +4 more
doaj +4 more sources
Pesquisa Veterinária Brasileira, 2014 The electrocardiography (ECG) QT interval is influenced by fluctuations in heart rate (HR) what may lead to misinterpretation of its length. Considering that alterations in QT interval length reflect abnormalities of the ventricular repolarisation which ...
Maira S. Oliveira +4 more
doaj +1 more source
The QT and Corrected QT Interval in Recovery After Exercise in Children [PDF]
Circulation: Arrhythmia and Electrophysiology, 2011 Background— Prolongation of the QT interval after exercise can be used to help diagnose long-QT syndrome, especially when the resting QT interval is borderline. The aim of this study was to determine the normal ranges for QT and corrected QT in the recovery phase after exercise in children ...
Berger, Wouter Rudolph +5 more
openaire +3 more sources
Prolonged QT Interval in Cirrhosis: Twisting Time?
Gut and Liver, 2022 Approximately 30% to 70% of patients with cirrhosis have QT interval prolongation. In patients without cirrhosis, QT prolongation is associated with an increased risk of ventricular arrhythmias, such as torsade de pointes (TdP).
William Lee +3 more
doaj +1 more source