Results 51 to 60 of about 55,874 (301)

Comparison of Four Rate-Correction Algorisms for the Ventricular Repolarization Period in Assessing Net Effects of IKr Blockers in Dogs

Journal of Pharmacological Sciences, 2006
The utility of corrected and uncorrected QT interval changes for assessing net repolarization delay by IKr (a rapid component of delayed rectifier K+ currents) blockers was assessed in halothane-anesthetized dogs using the electrocardiogram and ...
Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Keitaro Hashimoto   +3 more
doaj   +1 more source

Arrhythmic risk in elderly patients candidates to transcatheter aortic valve replacement. predicative role of repolarization temporal dispersion [PDF]

, 2019
Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities ...
Crapanzano, Davide, DI IORIO, Claudia, Fabietti, Marcella, Magri', Damiano, Mariani, MARCO VALERIO, Mastropietri, Fabiola, Moscucci, Federica, Parrotta, Ilaria, Piccirillo, Gianfranco, Sabatino, Teresa, Salvi, Nicolo', Vespignani, Giulia   +11 more
core   +1 more source

Dual‐Ligand Metal‐Organic Frameworks via In Situ Amidoxime Engineering for Selective Ion Separation

Advanced Functional Materials, EarlyView.
Inspired by microbial ion‐trapping mechanisms, a mild and universal strategy is developed to construct highly porous amidoxime‐functionalized MOFs. DFT calculations and molecular force measurements reveal that the dual‐ligand amidoxime configuration significantly strengthens Ga(III) affinity.
Zhifang Lv, Guixia Fan, Yun Bai, Guosheng Li, Peng Li, Wenjihao Hu, Yijun Cao, Wenshuai Yang, Daoguang Teng, Hongbo Zeng   +9 more
wiley   +1 more source

Molecular Surface Engineering of Sulfide Electrolytes with Enhanced Humidity Tolerance for Robust Lithium Metal All‐Solid‐State Batteries

Advanced Materials, EarlyView.
It is demonstrated that the electrochemical, interfacial, and humidity stability of halide‐doped sulfide electrolytes (LPSClBr) is significantly enhanced by an organic surface coating using octadecyl phosphonic acid (OPA) and its lithiated form (Li‐OPA). This single‐step strategy enables robust interfacial protection, supports lithium metal anodes, and
Laras Fadillah, Leonie Braks, Jihoon Oh, Mingliang Liu, Hanna Türk, Davide Tisi, Mounir Mensi, Michele Ceriotti, Jang Wook Choi, Ali Coskun   +9 more
wiley   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

The importance of the epinephrine provocation test for the hidden type-1 congenital long QT syndrome

Türk Kardiyoloji Derneği Arşivi, 2020
Congenital long QT syndrome (LQTS) is a genetic channelopathy associated with a high incidence of sudden cardiac death in children and young adults. QT interval prolongation is typically the primary finding on the electrocardiography (ECG) recordings ...
Adem Atici, Ramazan Asoğlu, Hasan Ali Barman, Irfan Sahin   +3 more
doaj   +1 more source

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

Therapeutic Advances in Psychopharmacology, 2022
Background: A prolonged electrocardiogram (ECG) QT interval is associated with cardiac events and increased mortality. Antipsychotics can prolong the QT interval.
Teodora Andric, Karl Winckel, Timothy David Tanzer, Samantha Hollingworth, Lesley Smith, Katherine Isoardi, Olivier Tan, Dan Siskind   +7 more
doaj   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Electrocardiogram alterations following one-week consumption of Crocus sativus L. (saffron) [PDF]

, 2012
Considering the global popularity and also the various biological and medicinal properties of saffron, this study was conducted to assess the influence of its aqueous extracts administration on blood pressure, pressure-rate product (PRP) and ...
Joukar, Siyavash
core  

Shortening of the Short Refractory Periods in Short QT Syndrome. [PDF]

, 2017
BACKGROUND: Diagnosis of short QT syndrome (SQTS) remains difficult in case of borderline QT values as often found in normal populations. Whether some shortening of refractory periods (RP) may help in differentiating SQTS from normal subjects is unknown.
Cardin, C, Fourcade, C, Gaita, F, Gandjbakhch, E, Giustetto, C, Maupain, C, Maury, P, Mondoly, P, Monteil, B, Rollin, A, Scrocco, C   +10 more
core   +3 more sources