Results 141 to 150 of about 4,680,147 (302)

Correction [PDF]

Journal of the American College of Cardiology, 2017
  +7 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The complex relationships among self-acceptance, perceived social support, drug use stereotype threat, and subthreshold depression in people with substance use disorder: exploring the mediating and buffering effects

Frontiers in Psychiatry
IntroductionDepression levels are significantly higher among people with substance use disorder (SUD) than in the general population; however, studies on the level of subthreshold depression in this population are scarce.
Yongqiu Li, Rufang Wang, Jun Liu, Zuoliang Li, Yinghua Zhou   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Corrections [PDF]

The Lancet Infectious Diseases, 2018
  +10 more sources

A protocol for a randomized comparison of extended-release versus sublingual buprenorphine among pre-trial detainees in jail

Addiction Science & Clinical Practice
Context/background The high prevalence of opioid use among jailed adults offers an unmatched opportunity to identify and treat those with opioid use disorder (OUD), a population that is at a substantial risk for post-release overdose.
Rebecca E. Rottapel, Thomas J. Stopka, Peter D. Friedmann, Randall A. Hoskinson Jr., Daviana Englander, Nicole Calhoun, Thomas Senst, Christopher Gudas, Peter J. Koutoujian, David Farabee   +9 more
doaj   +1 more source

Bayesian recalibration ofPlanckgalaxy cluster scaling relations including relativistic Sunyaev-Zel’dovich corrections [PDF]

Y. C. Perrott
openalex   +1 more source

Correction to: Enablers and barriers to implementing care quality improvement program in nursing homes in China [PDF]

, 2022
Yinan Zhao, Lulu Liao, Hui Feng, Huijing Chen, Hongting Ning   +4 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source