Results 61 to 70 of about 2,004,539 (278)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Connecticut Department of Correction statistics

open access: yes, 2008
Began in 2002?; Title from home page last modified 7/3/07 (viewed Dec.

core   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Corneal backscatter as a biomarker for edema severity in Fuchs endothelial corneal dystrophy: a cross-sectional study

open access: yesEye and Vision
Background Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive endothelial dysfunction and corneal edema. Reliable objective biomarkers for grading disease severity are currently evolving.
Maximilian Friedrich   +8 more
doaj   +1 more source

Department of Correction

open access: yes, 2008
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Dec. 7, 2010).; At head of title: State of Connecticut.; Harvested from the web on 12/7/10Official website of the Connecticut Department of Correction.

core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Molecular Changes in Aqueous Humor Associated with Inflammation Following Cataract Surgery in Patients with Fuchs’ Endothelial Corneal Dystrophy

open access: yesOphthalmology and Therapy
Introduction To evaluate the anterior chamber (AC) inflammation in the early postoperative period after cataract surgery and before Descemet membrane endothelial keratoplasty (DMEK) by quantifying oxidative stress and inflammatory mediators in aqueous ...
Lizaveta Chychko   +5 more
doaj   +1 more source

The clinical case of sildenafil administration in a very premature infant with pulmonary hypertension

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2015
We report the use of oral sildenafil in a 7-month-old preterm newborn with severe bronchopulmonary dysplasia and pulmonary arterial hypertension refractory to captopril and inhaled budesonide, and need of consistent oxygenation.
Galina A. Alyamovskaya   +3 more
doaj   +1 more source

Department of Correction

open access: yes, 2010
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Dec. 7, 2010).; At head of title: State of Connecticut.; Harvested from the web on 12/7/10Official website of the Connecticut Department of Correction.

core  

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