Results 71 to 80 of about 6,018,350 (361)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Core competency model self-directed violence prevention training program for corrections: a hybrid feasibility-effectiveness trial

BMC Public Health
Background Self-directed violence encompasses both suicide and self-injury. United States correctional settings face high self-directed violence rates.
Skyler D. Prowten, Sam C. Cacace, Jessamyn Moxie, Ava Peters, Adria Corral, Marvella Bowman, Lewis J. Peiper, Robert J. Cramer   +7 more
doaj   +1 more source

The Anharmonic Correction in the Soliton Model for the Hyperons

, 1994
We derive the anharmonic correction to the hyperon energy in the bound state version of the topological soliton model for the hyperons, and show that it represents a negative correction of at most 10% to the energy of the bound heavy flavour two-meson ...
Adkins, Björnberg, Björnberg, Blom, Callan, Callan, D.O. Riska, Jenkins, K. Dannbom, Kunz, M. Björnberg, Nyman, Oh, Oh, Pari, Pari, Pari, Rho, Rho, Riska, Riska, Schat, Scoccola, Skyrme   +23 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Scale-dependent correction to the dynamical conductivity of a disordered system at unitary symmetry

, 2012
Anderson localization has been studied extensively for more than half a century. However, while our understanding has been greatly enhanced by calculations based on a small epsilon expansion in d = 2 + epsilon dimensions in the framework of non-linear ...
Muttalib, K. A., Nakayama, T., Ostrovsky, P. M., Wölfle, P.   +3 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Correction to: Cartilage Endplate Stem Cells Inhibit Intervertebral Disc Degeneration by Releasing Exosomes to Nucleus Pulposus Cells to Activate Akt/Autophagy [PDF]

, 2023

openalex   +1 more source

Hybridization-related correction to the jellium model for fullerenes

, 2013
We introduce a new type of correction for a more accurate description of fullerenes within the spherically symmetric jellium model. This correction represents a pseudopotential which originates from the comparison between an accurate ab initio ...
A V Korol, A V Solov'yov, A V Verkhovtsev, Frisch M J, Kidun O, Madjet M E, Polozkov R G, R G Polozkov, Sattler K D, Solov'yov I A, V K Ivanov, Vieira A, Yabana K, Östling D   +13 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source