Results 71 to 80 of about 31,508 (267)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ALGORITHM FOR OPTIMAL CORRECTION OF TRAIN TRAFFIC SCHEDULE

TRANSPORT, 2006
The article analyses the problem of train traffic schedule optimal addition according to minimum overall expenditure criteria. The task is to analyze optimal insertion of an additional train track into already made schedule. The methodology is all‐right applicable for ad hoc requests submission.
Mišauskaitė, Indrė, Bagdonas, Vaclovas, Vilniaus Gedimino technikos universitetas, Lietuvos mokslų akademija   +3 more
openaire   +4 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Effect Rehabilitation Exercise on the Upper Crossed Syndrome in Patients with Coronary Artery Bypass Surgery

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2018
Introduction: Due to the importance of correct posture and the association of inappropriate posture with pain in the chest and scapula, the aim of this was to investigate the impact of rehabilitation exercise on the upper crossed syndrome in coronary ...
Farideh Babakhani, Mahdi Rahmani, Amir Hossein Barati   +2 more
doaj  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Effects of Two Corrective Protocols on Trunk Muscles in Females with Hyperlordosis; Williams vs McKenzie’s Protocol

Armaghane Danesh Bimonthly Journal, 2021
Background & aim: One of the most common causes of back deformities is spinal curve change in the waist. Physical therapy is one of the most common methods for treatment of lordosise and back pain.
Marziyeh Javid, Mohammadali Kazemi, Rouholah Fatemi   +2 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Corrective Exercise; Theraband Exercise; NASM; Water Resistance Training; Flat Foot

Journal of Ardabil University of Medical Sciences, 2021
Background & objectives: Flat foot is one of the most common physical and motor disorders among students. The aim of this study was to investigate the effects of three comprehensive corrective exercise protocols on the correction of flexible flat foot in
Abbas Mousavi, Allahyar Arabmomeni
doaj