Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Effect of Corrective Exercise vs Corrective Games on Upper Crossed Syndrome in Female Students
Purpose: This study aimed to compare the effect of corrective exercise and corrective games on upper crossed syndrome in female students. Methods: This was a quasi-experimental study performed with the pre-test and post-test method.
Abdolrasoul Daneshjoo +2 more
doaj
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Core Stability Training Improves Movement Quality, Balance, and Performance in Basketball Players [PDF]
Purpose: A strong core is a crucial prerequisite for participation in many sports. This study aimed to investigate the effect of core stability exercises on functional movement screen (FMS) scores, balance, and performance in elite basketball players ...
Amirreza Saeidizadeh +6 more
doaj
One of the key abilities in the game Kho Kho is tapping. Control of running speed, along with appropriate body balance and suppleness, are necessary for this tapping skill.
Pritha Srinivasan +4 more
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Importance of Eccentric Training in Corrective Exercises Continuum: Hints for Corrective Exercise Specialists [PDF]
Hashem Piri
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Effect of Ergonomic and Corrective Movement Interventions on Improving Sleep Quality and Reducing Musculoskeletal Disorders in Police Officers [PDF]
Introduction: Police officers often suffer from poor sleep quality and a high prevalence of musculoskeletal disorders due to shift work patterns and the physically and mentally demanding nature of their job. This study aimed to determine the effect of an
Rana Kaveh +2 more
doaj

