Results 101 to 110 of about 605,840 (270)
Automatically proving the correctness of vehicle coordination
ICT Express, 2018 In the next generation of road-based transportation systems, where vehicles exchange information and coordinate their actions, a major challenge will be to ensure that the interaction rules are safe and lead to progress.
Mikael Asplund
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
SOCIETY, SCIENCE, AND ECONOMICS: THE DELICATE BALANCE BETWEEN IDEOLOGY AND EPISTEMOLOGY AND THE CONCEPT OF FAIRNESS [PDF]
Ideological Dominance and Epistemological Relevance; Modelling and Theory Formulation; Instrumentalism; Free Market and Regulated Market; Theory of Imperfect Competition, Fairness, Consensual Correctness, Representational Correctness.
Stanley C. W. Salvary
core
The Normativity of Doxastic Correctness [PDF]
, 2018 It is widely maintained that doxastic norms that govern how people should believe can be explained by the truism that belief is governed by the correctness norm: believing p is correct if and only if p.
Ho, Tsung-Hsing
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Metric-based method of software requirements correctness improvement
ITM Web of Conferences, 2017 The work highlights the most important principles of software reliability management (SRM). The SRM concept construes a basis for developing a method of requirements correctness improvement.
Yaremchuk Svitlana +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source