Results 91 to 100 of about 2,493,519 (340)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Compiler-aided Type Tracking for Correctness Checking of MPI Applications

open access: yes, 2018
MUST, a dynamic MPI correctness checker, is extended with a type and memory allocation tracking sanitizer called TypeART for C/C++ codes based on the LLVM compiler framework.
Protze, Joachim   +13 more
core   +1 more source

Thinking of Political Correctness With Its Opposite: Anti – Political Correctness

open access: yes, 2023
1960’ların sonlarında Amerikan Üniversitelerinde ilk olarak ortaya çıktığında Politik doğruculuk kavramı, en genel haliyle konuşurken ve davranışlarımızla başta etnik, dinsel, kültürel ve cinsel azınlıkları olmak üzere başkalarını incitecek ifade ve ...
Kumtepe, Mehmet Akif   +1 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Reasoning about Protocols using Dijkstra’s Calculus

open access: yesJournal of Computer Science and Technology, 2004
A mathematical model for the specification and verification of a data link layer protocol is proposed. The weakest precondition calculus, developed by Dijkstra, originally for sequential programs, has been chosen for this purpose. It is demonstrated that
Awadhesh Kumar Singh   +1 more
doaj  

Validation of an in vitro biological method for filgrastim potency assessment

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Filgrastim is a human granulocyte colony-stimulating factor produced using recombinant DNA technology. Since filgrastim quality control necessitates a validated method, establishing the entire method validation parameters is of high ...
L. A. Gaiderova   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

On correctness of buffer implementations in a concurrent lambda calculus with futures

open access: yes, 2009
Motivated by the question of correctness of a specific implementation of concurrent buffers in the lambda calculus with futures underlying Alice ML, we prove that concurrent buffers and handled futures can correctly encode each other.
Sabel, David   +3 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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