Results 71 to 80 of about 605,840 (270)

Political Correctness [PDF]

open access: yes
An informed advisor wishes to convey her valuable information to an uninformed decision maker with identical preferences. Thus she has a current incentive to truthfully reveal her information.
Stephen Morris
core  

Verified Correctness and Security of mbedTLS HMAC-DRBG

open access: yes, 2017
We have formalized the functional specification of HMAC-DRBG (NIST 800-90A), and we have proved its cryptographic security--that its output is pseudorandom--using a hybrid game-based proof.
Almeida José Bacelar   +8 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Reasoning about Protocols using Dijkstra’s Calculus

open access: yesJournal of Computer Science and Technology, 2004
A mathematical model for the specification and verification of a data link layer protocol is proposed. The weakest precondition calculus, developed by Dijkstra, originally for sequential programs, has been chosen for this purpose. It is demonstrated that
Awadhesh Kumar Singh   +1 more
doaj  

Validation of an in vitro biological method for filgrastim potency assessment

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Filgrastim is a human granulocyte colony-stimulating factor produced using recombinant DNA technology. Since filgrastim quality control necessitates a validated method, establishing the entire method validation parameters is of high ...
L. A. Gaiderova   +5 more
doaj   +1 more source

Validate implementation correctness using simulation: the TASTE approach [PDF]

open access: yes, 2012
High-integrity systems operate in hostile environment and must guarantee a continuous operational state, even if unexpected events happen. In addition, these systems have stringent requirements that must be validated and correctly translated from high ...
Delange, Julien   +2 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

On Computing Minimum Unsatisfiable Cores [PDF]

open access: yes, 2003
Certifying the correctness of a SAT solver is straightforward for satisfiable instances of SAT. Given
Lynce, I., Marques-Silva, J. P.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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