Results 81 to 90 of about 2,493,519 (340)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Political Correctness: Implosion of Politics
Philosophies, 2017 The purpose of this article is to develop a critical understanding of political correctness as regressive process of incrimination based on a utopia of non-differentiation.
Alexis Dirakis
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Correctness of Closure Collapsing (appendix to conference submission) [PDF]
, 2006 A description in the Jacobs and Langen domain is a set of sharing groups where each sharing group is a set of program variables. The presence of a sharing group in a description indicates that all the variables in the group can be bound to terms that ...
Li, Xuan +5 more
core +1 more source
ON CORRECTNESS OF BAYES FORMULA
Advanced Engineering Research, 2014 The inadmissibility of the comparison and cooperative processing of the conditional probabilities calculated with the use of the known variations of Bayes formula considering a well-defined amount of the accumulated evidences is established.
Alexander Ivanovich Dolgov
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Images, 2016 Cinema under pressure The article contains a synthetic look at the issue of film censorship, taking into account its various forms. The author combines the perspective of a contemporary synchronous with the diachronic perspective, dating back to the ...
MAREK HENDRYKOWSKI
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Verifying Probabilistic Correctness in Isabelle with pGCL [PDF]
Electronic Proceedings in Theoretical Computer Science, 2012 This paper presents a formalisation of pGCL in Isabelle/HOL. Using a shallow embedding, we demonstrate close integration with existing automation support.
David Cock
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source