Results 51 to 60 of about 1,393,629 (304)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Jackknife Empirical Likelihood for Chatterjee's Rank Correlation Coefficient
Chatterjee’s rank correlation coefficient (CCC) is a rank correlation coefficient that estimates a population quantity while remaining asymptotically normal under independence.
Amusa, Tope
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Coefficient of Structural Concordance and an Example of its Application: Labour Productivity and Wages in Slovenia [PDF]
The article presents the underlying principles, derivation and properties of a simple descriptive measure of concordance between two analogous rank structures that we call the coefficient of structural concordance.
Miroslav Verbič, Franc Kuzmin
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015 In article the mathematico-statistical analysis of quality of dough on the subject "Linear Algebra, Analytical Geometry" is carried out. Quality of dough decides on the help of such characteristics as reliability, a validity and a diskriminativnost.
Larisa V. Limanova +1 more
doaj
A Robust measure for the correlation coefficient
, 2007 In this paper, we investigate the robustness of some well known correlation coefficients, namely, Pearson's, Spearman's and Kendall's. The empirical evidence shows that these correlation coefficients are sufficiently non-robust against outliers. That is,
El-Salam, Moawad El-Fallah Abd
core
Intraclass-correlation coefficient (ICC).
, 2020 Intraclass-correlation coefficient (ICC).
Patrick Robert Kircher (8394153) +4 more
core +1 more source