Results 101 to 110 of about 196,680 (343)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Theoretical Framework For The Design Of Purely Real Synthetic-Discriminant-Function-Type Correlation Filters

open access: yes, 1992
A general algorithm for synthesizing purely real correlation filters in the frequency domain is developed by using the method of Lagrange multipliers.
Mahalanobis, Abhijit, Song, Sewoong
core   +2 more sources

Accurate depth from defocus estimation with video-rate implementation [PDF]

open access: yes
The science of measuring depth from images at video rate using „defocus‟ has been investigated. The method required two differently focussed images acquired from a single view point using a single camera.
Raj, Alex Noel Joseph
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Robustness of the nonlinear filter: the correlated case

open access: yesStochastic Processes and their Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bhatt, Abhay G., Karandikar, Rajeeva L.
openaire   +2 more sources

Morphological filters for functional assessment of roundness profiles

open access: yes, 2014
Filtration techniques are useful tools of analysing roundness profiles. The 2RC filter and Gaussian filter are commonly used to assess peripheral undulations of the roundness data.
Lou, Shan   +6 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hardware design of correlation filters for target detection

open access: yes, 2019
Correlation filters have been implemented in software and have proven very effective for automatic target detection, biometric verification and security applications.
Naeem Akbar (16274135)   +4 more
core   +1 more source

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