Results 21 to 30 of about 62,637 (226)

Basic methodical principles in introducing children to the environment [PDF]

open access: yesSinteze, 2012
Through interaction with people and the environment a child learns about the world around him, becomes involved in the real world and constructs his own identity.
Mihajlović Nevenka   +1 more
doaj  

Impacts of AIOT Implementation Course on the Learning Outcomes of Senior High School Students

open access: yesEducation Sciences, 2021
In this study, experimental teaching was conducted through the artificial intelligence of things (AIOT) practical course, and the 4D (discover, define, develop, deliver) double diamond shape was used to design the course and plan the teaching content to ...
Chih-Cheng Tsai   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

CORRELATION OF MUSIC AND ART CULTURE TEACHING CONTENT

open access: yesSCIENCE International Journal
The paper discusses the correlation of the content of teaching music and fine arts in the lower grades of elementary school. The goal of this research was to determine how the connection between the elements of music and visual arts can be used in working with students within these two subjects. Given the natural connection of related teaching contents
Dragana Cicović Sarajlić   +2 more
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Geography and history lessons at museum and archive

open access: yesRevija za Geografijo, 2021
The article presents some characteristics of teaching in museums and archives and highlights the positive effects of such teaching on pupils and students.
Andreja Lajh, Eva Konečnik Kotnik
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Entrepreneurship education and entrepreneurship intention among business administration students, Ambrose Alli university, Ekpoma, Edo State, south-south of Nigeria

open access: yesХабаршысы. Экономика сериясы, 2023
This study examined how entrepreneurship education affected students of business administration at Ambrose Alli University, Ekpoma, Nigeria's South-South geopolitical zone to become entrepreneurs. Survey research design was adopted in the study.
Ugbomhe O. Ugbomhe, P. A. Akhator
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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