Results 81 to 90 of about 556,953 (307)
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
From correspondence analysis to multiple and joint correspondence analysis [PDF]
The generalization of simple (two-variable) correspondence analysis to more than two categorical variables, commonly referred to as multiple correspondence analysis, is neither obvious nor well-defined.
Michael Greenacre
core
Kitcher, Correspondence, and Success [PDF]
, 2004 Concerned that deflationary theories of truth threaten his scientific realism, Philip Kitcher has constructed an argument that scientific success establishes not only the truth of crucial scientific beliefs but also their *correspondence* truth.
Whitcomb, Dennis
core
On the ODE/IM correspondence for minimal models [PDF]
, 2008 Within the framework of the ODE/IM correspondence, we show that the minimal conformal field theories with c < 1 emerge naturally from the monodromy properties of certain families of ordinary differential ...
Dunning, Clare +3 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A revamped understanding of Cosmic Rays and Gamma-Ray Bursts
Physics Letters BInteresting data on Gamma Ray Burts (GRBs) and Cosmic Rays (CRs) have recently been made public. GRB221009A has a record “peak energy”. The CR electron spectrum has been measured to unprecedented high energies and exhibits a “knee” akin to the ones in ...
A. De Rújula
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Subset correspondence analysis: Visualizing relationships among a selected set of response categories from a questionnaire survey [PDF]
It is shown how correspondence analysis may be applied to a subset of response categories from a questionnaire survey, for example the subset of undecided responses or the subset of responses for a particular category.
Rafael Pardo, Michael Greenacre
core