Results 121 to 130 of about 1,726 (150)
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Corrinoid and thiol dependent threonine decarboxylation
Biochemical and Biophysical Research Communications, 1976Summary A novel system for the decarboxylation of L-threonine requiring the presence of certain aquocorrinoids, preferably diaquocobyric acid, and of a thiol is described. The reaction shows a marked optimum at a pH value of about 8. Other L-amino acids, with the exception of L-serine, are much less reactive. Optical data point to a ligand attachment
S H, Ford, H C, Friedmann
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Analysis of corrinoids in ovine tissues
Biomedical Chromatography, 2005AbstractCorrinoids from various ovine tissue samples (liver, blood, small intestinal fluid and faeces) were analysed using a combination of high‐performance liquid chromatography (HPLC) and a radioisotope dilution assay (RIDA) to estimate the distribution of corrinoids—the cobalamins hydroxocobalamin (OH‐cbl), methylcobalamin (me‐cbl) and 5 ...
Kelly, R J +3 more
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Cobalt-free Corrinoids as Vitamin B12 Antagonists
Nature, 1966Abstract The anti-vitamin B12 properties of four descobalto-corrins isolated from Chromatium cells were compared with vitamin B12-anilide, vitamin B12-monocarboxylic acid, cobinamide, and Friedrich's C′3-2-methyl-2-aminopropanol(1)-vitamin B12 (compound S-102).
D, Perlman, J I, Toohey
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Journal of Molecular Structure: THEOCHEM, 1998
Abstract NMR-restrained molecular dynamics (MD) and simulated annealing (SA) calculations have been performed on cyanocobalamin (CNCbl, vitamin B 12 ), and three methylcobalt corrinoids, the coenzymatically active methylcobalamin (CH 3 Cbl), and two analogs of its base-off species, methylcobinamide (CH 3 Cbi + ), which lacks an axial nucleotide, and ...
Kenneth L Brown +2 more
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Abstract NMR-restrained molecular dynamics (MD) and simulated annealing (SA) calculations have been performed on cyanocobalamin (CNCbl, vitamin B 12 ), and three methylcobalt corrinoids, the coenzymatically active methylcobalamin (CH 3 Cbl), and two analogs of its base-off species, methylcobinamide (CH 3 Cbi + ), which lacks an axial nucleotide, and ...
Kenneth L Brown +2 more
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Cobalt and Corrinoid Transport and Biochemistry
2012In this chapter, we focus on the biochemistry of non-corrin cobalt and on a subset of corrinoid-containing enzymes. We review the import of cobalt in prokaryotes and discuss two members of the non-corrin cobalt-dependent enzymes, nitrile hydratase and methionine aminopeptidase.
Valentin, Cracan, Ruma, Banerjee
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Cobalamin- and Corrinoid-Dependent Enzymes
2009This chapter reviews the literature on cobalamin- and corrinoid-containing enzymes. These enzymes fall into two broad classes, those using methylcobalamin or related methylcorrinoids as prosthetic groups and catalyzing methyl transfer reactions, and those using adenosylcobalamin as the prosthetic group and catalyzing the generation of substrate ...
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Complex Samples Cyanide Detection with Immobilized Corrinoids
ACS Applied Materials & Interfaces, 2012Colorimetric solid phase with spatially separated extraction and detection zones as a rapid, effective and economic method for the optical detection of cyanide in complex samples is described. The system is seven times more sensitive for the optical detection of cyanide than the same class of chemical sensors used under homogeneous conditions.
Christine, Männel-Croisé +1 more
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Journal of the American Chemical Society, 1993
Coenzyme B 12 analogs α-neopentylcobinamide (α-NpCbi + ) and α-neopentylcobalamin (α-NpCbl), where the bulky organic ligand is in the «lower» (α) axial ligand position, have been synthesized by reductive alkylation of cyanoaquocobinamide and aquocobalamin, respectively, with neopentyl bromide at ∼0 o C, and characterized by their UV-visible spectra ...
Xiang Zou, Kenneth L. Brown
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Coenzyme B 12 analogs α-neopentylcobinamide (α-NpCbi + ) and α-neopentylcobalamin (α-NpCbl), where the bulky organic ligand is in the «lower» (α) axial ligand position, have been synthesized by reductive alkylation of cyanoaquocobinamide and aquocobalamin, respectively, with neopentyl bromide at ∼0 o C, and characterized by their UV-visible spectra ...
Xiang Zou, Kenneth L. Brown
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Corrinoid catalysis of thiol oxidation
Inorganica Chimica Acta, 1983Abstract Under appropriate conditions, thiols can react with corrinoids to form relatively stable complexes [1–7], or reduced corrinoids [1, 2, 8–11]. If alkyl halides are present during the reduction of corrinoids by thiols, alkyl corrinoids are produced [4, 9, 12, 13].
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Multiple Functions of Corrinoids in Prokaryote Biology
Applied Biochemistry and Microbiology, 2003Data on more than 30 metabolic processes and biochemical reactions, involving corrinoids, which have been described in prokaryotes thus far, are reviewed. These pathways (central or specific, catabolic or anabolic) are inherent in bacteria and archebacteria of diverse phylogenetic lineages, comprising several physiological groups.
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