Novel Pathway for Corrinoid Compounds Production in Lactobacillus [PDF]
Frontiers in Microbiology, 2018 Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Andrea Carolina Torres +4 more
doaj +10 more sources
Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches [PDF]
mBio, 2023 The ability to sense and respond to intracellular metabolite levels enables cells to adapt to environmental conditions. Many prokaryotes use riboswitches—structured RNA elements usually located in the 5′ untranslated region of mRNAs—to sense ...
Rebecca R. Procknow +4 more
doaj +2 more sources
Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins [PDF]
eLife, 2018 Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Aaron G Wexler +5 more
doaj +3 more sources
Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT. [PDF]
PLoS ONE, 2016 A cobalamin (Cbl) cofactor in corrinoid iron-sulfur protein (CoFeSP) is the primary methyl group donor and acceptor in biological carbon oxide conversion along the reductive acetyl-CoA pathway.
Peer Schrapers +6 more
doaj +9 more sources
Frontiers in Microbiology, 2015 De novo corrinoid biosynthesis represents one of the most complicated metabolic pathways in nature. Organohalide-respiring bacteria (OHRB) have developed different strategies to deal with their need of corrinoid, as it is an essential cofactor of ...
Aamani eRupakula +6 more
doaj +3 more sources
Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex [PDF]
Communications Biology, 2023 Structures of Methanosarcina barkeri trimethylamine methyltransferase (MttB) with its substrates reveal the role of pyrrolysine in methyl group transfer from trimethylamine to the corrinoid cofactor in MttC.
Jiaxin Li +6 more
doaj +2 more sources
Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth [PDF]
Journal of BacteriologyBacteria encounter chemically similar nutrients in their environment, which impact their growth in distinct ways. Among such nutrients are cobamides, the structurally diverse family of cofactors related to vitamin B12 (cobalamin), which function as ...
Kenny C. Mok +3 more
doaj +2 more sources
Methanogenesis from tetramethylammonium and choline in Methanococcoides methylutens Q3c requires a nonpyrrolysine monomethylamine methyltransferase homolog [PDF]
Frontiers in MicrobiologyMethanogenesis is a key biological process contributing to both global climate change and renewable energy via methane. Methylotrophic methanogenesis is an important, but often underappreciated, component of this process.
Jyoti Kashyap +6 more
doaj +2 more sources
Methanogenic activities signatures in broilers fed black soldier fly (Hermetia illucens) larvae-based diets [PDF]
Biochemistry and Biophysics ReportsMethanogenic archaea in the avian gut contribute to hydrogen turnover and thus play a role in fermentative efficiency and greenhouse gas emission. While black soldier fly larvae meal (BSFLM) has been explored as a replacement for fishmeal in broiler ...
Deborah Oluwaferanmi Ibiwoye +6 more
doaj +2 more sources
Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates [PDF]
Frontiers in Microbiology, 2016 The genomes of two closely related Dehalobacter strains (strain CF and strain DCA) were assembled from the metagenome of an anaerobic enrichment culture that reductively dechlorinates chloroform (CF), 1,1,1-trichloroethane (1,1,1-TCA) and 1,1 ...
Shuiquan eTang +6 more
doaj +2 more sources