Results 11 to 20 of about 3,608 (195)

Genomic potential for mercury biotransformation in marine sediments across marginal slope to hadal zone [PDF]

Nature Communications
Mercury accumulates in the deep sea, but its ecological impact on deep-sea ecosystems remains poorly understood. We conduct an analysis of 32 sediment cores, comprising 101 layers for the study of metagenomes, and additional 41 global reference sediment ...
Zhuobo Li, Taoshu Wei, Lisheng He, Haifeng Qian, Yong-Guan Zhu, Yong Wang   +5 more
doaj   +2 more sources

Skin-associated Corynebacterium amycolatum shares cobamides [PDF]

mSphere
The underlying interactions that occur to maintain skin microbiome composition, function, and overall skin health are largely unknown. Often, these types of interactions are mediated by microbial metabolites.
M. H. Swaney, N. Henriquez, T. Campbell, J. Handelsman, L. R. Kalan   +4 more
doaj   +2 more sources

Site-specific incorporation of 19F-nuclei at protein C-terminus to probe allosteric conformational transitions of metalloproteins [PDF]

Communications Biology
Allosteric conformational change is an important paradigm in the regulation of protein function, which is typically triggered by the binding of small cofactors, metal ions or protein partners.
Xichun Liu, Pengfei Guo, Qiufan Yu, Shu-Qin Gao, Hong Yuan, Xiangshi Tan, Ying-Wu Lin   +6 more
doaj   +2 more sources

Vitamin B12 and Reproductive Health: Clinical Insights, Emerging Mechanistic Understanding, and Nutritional Aspects. [PDF]

Mol Reprod Dev
ABSTRACT Epidemiological data from assisted reproductive technologies (ART) link vitamin B12 (VitB12) deficiency to shorter gestation, low birth weight, and reduced live birth rates. VitB12 also plays a critical role in fertility for both sexes by supporting gamete quality.
Mathew AR, Selita E, Regano C, Bianco C, Corsetti V, Cavallucci V, Moreno S, Tata AM, Fidaleo M.   +8 more
europepmc   +2 more sources

Pseudovitamin B₁₂ producing Loigolactobacillus coryniformis enhances soy milk fermentation by Lactobacillus delbrueckii subsp. bulgaricus. [PDF]

J Sci Food Agric
Abstract BACKGROUND Fermenting soy milk with lactic acid bacteria is challenging. Generally, carbohydrates are added to enhance the acid production in soy milk. However, the yoghurt starter Lactobacillus delbrueckii subsp. bulgaricus did not succeed in fermenting soy milk supplemented with carbohydrates.
Tsuda H, Iwai K, Hayashizaki N.
europepmc   +2 more sources

Comparative Physiology and Genomics of Thermincola and Carboxydocella Strains and Description of Two Novel Isolates. [PDF]

Environ Microbiol
Two novel thermophilic bacteria, Thermincola strain AZ34E and Carboxydocella strain AZ29I, were isolated from hydrothermal environments and shown to oxidise carbon monoxide via the water‐gas shift reaction. Comparative genomic and phylogenetic analyses revealed that all currently described isolates within Thermincola and Carboxydocella each represent a
Galani A, Antony Venancius M, Sipkema D, Sousa DZ.   +3 more
europepmc   +2 more sources

Cobalamin Riboswitches Are Broadly Sensitive to Corrinoid Cofactors to Enable an Efficient Gene Regulatory Strategy

mBio, 2022
In bacteria, many essential metabolic processes are controlled by riboswitches, gene regulatory RNAs that directly bind and detect metabolites. Highly specific effector binding enables riboswitches to respond to a single biologically relevant metabolite.
Kristopher J. Kennedy, Florian J. Widner, Olga M. Sokolovskaya, Lina V. Innocent, Rebecca R. Procknow, Kenny C. Mok, Michiko E. Taga   +6 more
doaj   +1 more source

Corrinoids in anaerobic bacteria [PDF]

FEMS Microbiology Letters, 1990
C1-metabolizing bacteria were analyzed for their corrinoids. The autotrophic phototrophe Chloroflexus aurantiacus contains predominantly the light-sensitive coenzyme B12. The corrinoid could be teh prostethic group of a methylmalonyl-CoA mutase, which is involved in the CO2 fixing reaction sequence from proplonyl-CoA to succinyl CoA.
Erhard Stupperich, Hans-Jürgen Eisinger, Sabine Schurr   +2 more
openaire   +2 more sources

Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities [PDF]

Environmental Microbiology, 2014
Summary Cobalamin and other corrinoids are essential cofactors for many organisms. The majority of microbes with corrinoid‐dependent enzymes do not produce corrinoids de novo , and instead must acquire corrinoids produced by other organisms in their environment. However, the
Men, Yujie, Seth, Erica C, Yi, Shan, Crofts, Terence S, Allen, Robert H, Taga, Michiko E, Alvarez-Cohen, Lisa   +6 more
openaire   +4 more sources

Evidence for corrin biosynthesis in the last universal common ancestor. [PDF]

FEBS J
Cobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Modjewski LD, Karavaeva V, Mrnjavac N, Knopp M, Martin WF, Sousa FL.   +5 more
europepmc   +2 more sources