Microbes display broad diversity in cobamide preferences [PDF]
MSystemsCobamides, the vitamin B12 (cobalamin) family of cofactors, are used by most organisms but produced by only a fraction of prokaryotes, and are thus considered key shared nutrients among microbes.
Hans Carlson, Kenny Mok, Michiko Taga
exaly +8 more sources
Cobamide metabolism, regulation, and adaptation in Mycobacterium tuberculosis [PDF]
Journal of BacteriologyCobamides play a paradoxical but critical role in the biology of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. Although Mtb retains nearly all cobalamin (Cbl) biosynthetic genes and encodes multiple cobamide-requiring enzymes ...
Terry Kipkorir +4 more
doaj +4 more sources
Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth [PDF]
Journal of BacteriologyBacteria encounter chemically similar nutrients in their environment, which impact their growth in distinct ways. Among such nutrients are cobamides, the structurally diverse family of cofactors related to vitamin B12 (cobalamin), which function as ...
Kenny C. Mok +3 more
doaj +4 more sources
Cobamide Sharing Is Predicted in the Human Skin Microbiome [PDF]
mSystems, 2022 The skin microbiome is a key player in human health, with diverse functions ranging from defense against pathogens to education of the immune system.
Mary Hannah Swaney +2 more
doaj +4 more sources
Nutrient smuggling: Commensal gut bacteria‐derived extracellular vesicles scavenge vitamin B12 and related cobamides for microbe and host acquisition [PDF]
Journal of Extracellular Biology, 2022 The processes by which bacteria proactively scavenge essential nutrients in crowded environments such as the gastrointestinal tract are not fully understood.
Rokas Juodeikis +7 more
doaj +3 more sources
Corrinoid salvaging and cobamide remodeling in bacteria and archaea [PDF]
Journal of BacteriologyABSTRACT Cobamides (Cbas) are cobalt-containing cyclic tetrapyrroles used by cells from all domains of life as co-catalyst of diverse reactions. There are several structural features that distinguish Cbas from one another.
Jorge C Escalante-Semerena +1 more
exaly +4 more sources
Cofactor binding interactions with reductive dehalogenase shape cobamide utilization in organohalide-respiring bacteria [PDF]
Communications BiologySelective utilization of certain cobamides, the vitamin B12-family enzyme cofactors, is a common physiological trait in organohalide respiration, an essential biogeochemical process relevant to global halogen cycling and the bioremediation of chlorinated
Huijuan Jin +10 more
doaj +2 more sources
A cooperative cobalamide biosynthesis guild in the endosphere of the edible aquatic plant Wolffia globosa Mankai [PDF]
Environmental MicrobiomeBackground Cobalamin (vitamin B₁₂) is synthesized only by certain bacteria and archaea and is rarely found in plant-derived foods because plants neither synthesize nor require this cofactor.
Rhishika Dutta +6 more
doaj +2 more sources
Cobamide-producing microbes as a model for understanding general nutritional interdependencies in soil food webs [PDF]
Nature CommunicationsNutrient crossfeeding critically governs microbiome–host interactions and ecosystem stability. Cobamides, synthesized only by prokaryotes, offer a powerful and tractable model for studying nutrient-mediated interdependencies in soil food webs; however ...
Qi Zhang +15 more
doaj +2 more sources
Complete genomes from a xenic Dolichospermum flosaquae FBCC-A233 culture reveal genome-inferred metabolic asymmetry with associated bacteria [PDF]
Microbiology SpectrumCyanobacteria form phycosphere communities with associated bacteria, but genome-resolved resources are needed to formulate testable hypotheses about their metabolic interactions.
Jina Kim +9 more
doaj +2 more sources