Results 21 to 30 of about 3,608 (195)
Four families of folate-independent methionine synthases.
PLoS Genetics, 2021 Although most organisms synthesize methionine from homocysteine and methyl folates, some have "core" methionine synthases that lack folate-binding domains and use other methyl donors.
Morgan N Price +2 more
doaj +1 more source
Expansion of cagA Copy Number in Helicobacter pylori During Co-Infection in a Mouse Model. [PDF]
HelicobacterABSTRACT Introduction The virulence factor CagA is critical in mediating inflammation, and Helicobacter pylori PMSS1 dynamically modulates cagA copy number in response to host immune pressure. Co‐infection with Salmonella enterica serotype Typhimurium has been shown to heighten systemic inflammation and reduce H.
Tissera K +7 more
europepmc +2 more sources
Water Science and Technology, 2022 Complete dechlorination of trichloroethene (TCE) by Dehalococcoides mccartyi is catalyzed by reductive dehalogenases (RDases), which possess cobalamin as the crucial cofactor. However, virtually all D. mccartyi isolated thus far are corrinoid auxotrophs.
Haijun Li +4 more
doaj +1 more source
Frontiers in Microbiology, 2020 Chlordecone (Kepone®) and γ-hexachlorocyclohexane (γ-HCH or lindane) have been used for decades in the French West Indies (FWI) resulting in long-term soil and water pollution. In a previous work, we have identified a new Citrobacter species (sp.86) that
Agnès Barbance +11 more
doaj +1 more source
The 380 kb pCMU01 plasmid encodes chloromethane utilization genes and redundant genes for vitamin B12- and tetrahydrofolate-dependent chloromethane metabolism in Methylobacterium extorquens CM4: a proteomic and bioinformatics study. [PDF]
PLoS ONE, 2013 Chloromethane (CH3Cl) is the most abundant volatile halocarbon in the atmosphere and contributes to the destruction of stratospheric ozone. The only known pathway for bacterial chloromethane utilization (cmu) was characterized in Methylobacterium ...
Sandro Roselli +3 more
doaj +1 more source
Structure of a membrane-bound menaquinol:organohalide oxidoreductase
Nature Communications, 2023 Organohalide-respiring bacteria are key organisms for the bioremediation of soils and aquifers contaminated with halogenated organic compounds. The major players in this process are respiratory reductive dehalogenases, corrinoid enzymes that use ...
Lorenzo Cimmino +7 more
doaj +1 more source
Nutrient cross-feeding in the microbial world. [PDF]
, 2014 The stability and function of a microbial community depends on nutritional interactions among community members such as the cross-feeding of essential small molecules synthesized by a subset of the population.
Seth, Erica C, Taga, Michiko E
core +2 more sources
Scientific Reports, 2023 Despite the success of AlphaFold2 (AF2), it is unclear how AF2 models accommodate for ligand binding. Here, we start with a protein sequence from Acidimicrobiaceae TMED77 (T7RdhA) with potential for catalyzing the degradation of per- and polyfluoroalkyl ...
Hao-Bo Guo +12 more
doaj +1 more source
Microorganisms, 2023 Targeted mutations in the anaerobic methylotroph Eubacterium limosum have previously been obtained using CRISPR-based mutagenesis methods.
James Millard +4 more
doaj +1 more source
Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]
, 2017 B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian +6 more
core +1 more source