Results 111 to 120 of about 53,540 (338)

Intravenous ketamine for subacute treatment of refractory chronic migraine: a case series. [PDF]

, 2016
BACKGROUND: Refractory migraine is a challenging condition with great impact on health related quality of life. Intravenous (IV) ketamine has been previously used to treat various refractory pain conditions.
Ashina, Sait, Lauritsen, Clinton, Lipton, Richard B., Mazuera, Santiago   +3 more
core   +3 more sources

Food for Thought: A Systematic Review and Meta‐Analysis on the Effects of Ultra‐Processed Foods on Cognition in Children and Adolescents

Food Frontiers, EarlyView.
Across 35 studies, this systematic review and meta‐analysis explored the link between ultra‐processed foods (UPFs) and cognition. For children, higher consumption of UPFs was associated with poorer attention, executive functioning, fluid intelligence, and language; for adolescents, higher UPF consumption was associated with poorer executive functioning,
Lan Nguyen, Jared Walters, Bernadette Spies, Amelia Coppus, Jenaya Massie, Thamiris Penteado Bertonha   +5 more
wiley   +1 more source

Evidence for orexinergic mechanisms in migraine

Neurobiology of Disease, 2015
Objective: To examine the effect of the orexinergic blockade with a dual orexin receptor antagonist (DORA) on experimental models of peripheral and central trigeminal as well as cortical activation relevant to migraine and migraine aura. Methods: In this
Jan Hoffmann, Weera Supronsinchai, Simon Akerman, Anna P. Andreou, Christopher J. Winrow, John Renger, Richard Hargreaves, Peter J. Goadsby   +7 more
doaj  

Cholinergic modulation of epileptiform activity in the developing rat neocortex [PDF]

, 1989
The effects of carbachol on picrotoxin-induced epileptiform activity and membrane properties of neurons in the developing rat neocortex were examined in an in vitro slice preparation.
Ben-Ari, Benardo, Bernd Sutor, Donoghue, Ferguson, Gutnick, Gähwiler, Haas, Haas, Hablitz, Hablitz, Hablitz, Halliwell, Hounsgaard, John J. Hablitz, Johnston, Kriegstein, Kriegstein, Krnjevic, Krnjevic, Lamour, Lamour, Madison, McCormick, McCormick, McLennan, Metherate, North, Pennefather, Sikes, Stone, Strejckova, Traub, Valentino, Vogt, Yamamoto   +35 more
core   +1 more source

Intelligent flexible memristors for artificial synapses and neuromorphic computing

FlexMat, EarlyView.
Overview of the Structure and Principle, Research Status, and Application Prospects of Flexible Memristor Materials (All relevant copyrights are listed in the following text). Abstract Memristors have garnered significant attention in the field of non‐volatile memory devices due to their excellent characteristics such as miniaturization, low power ...
Qingyao Mao, Zhenqian Zhu, Jialin Meng, Tianyu Wang   +3 more
wiley   +1 more source

Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5

Neuropsychiatric Disease and Treatment, 2016
Emanuela Viggiano,1,2 Vincenzo Monda,1 Antonietta Messina,1 Fiorenzo Moscatelli,3 Anna Valenzano,3 Domenico Tafuri,4 Giuseppe Cibelli,3 Bruno De Luca,1 Giovanni Messina,1,3 Marcellino Monda1 1Department of Experimental Medicine, Section of Human ...
Viggiano E, Monda V, Messina A, Moscatelli F, Valenzano A, Tafuri D, Cibelli G, De Luca B, Messina G, Monda M   +9 more
doaj  

Susceptibility Weighted Imaging as a Biomarker for Cortical Spreading Depression

Clinical and Translational Neuroscience
Introduction: Cortical spreading depression (CSD) is thought to be the pathophysiologic correlate of migraine aura. In experimental animals, CSD was shown to cause an increase in oxyhemoglobin.
Adrian Scutelnic, Isabelle Dominique Stöckli, Antonia Klein, Franz Riederer, Nedelina Slavova, Christoph J. Schankin   +5 more
doaj   +1 more source

The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization

PAIN Reports, 2018
. Introduction:. Cortical spreading depression (CSD) is believed to promote migraine headache by enhancing the activity and mechanosensitivity of trigeminal intracranial meningeal afferents.
Jun Zhao, Dan Levy
doaj   +1 more source

Perfusion Fixation With Glutaraldehyde and Post-Fixation With Osmium Tetroxide for Electron Microscopy [PDF]

, 1968
The conductivity of cerebral cortex drops during perfusion with glutaraldehyde in 5 min to about 60% of the original value, to remain unchanged during the subsequent 10-15 min of perfusion.
Khattab, F. I., van Harreveld, A.
core  

Glial Versus Neuronal Na+/K+‐ATPase in Activity‐Evoked K+ Clearance and Their Sensitivity to Elevated Extracellular K+

Glia, EarlyView.
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen, Brian Roland Larsen, Afnan Bilal Ghazal, Adriana Katz, K. C. Brennan, Steven J. D. Karlish, Nanna MacAulay   +6 more
wiley   +1 more source