Results 131 to 140 of about 53,540 (338)
The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi+2 more
wiley +1 more source
Migraine preventive drugs differentially affect cortical spreading depression in rat
Cortical spreading depression (CSD) is the most likely cause of the migraine aura. Drugs with distinct pharmacological properties are effective in the preventive treatment of migraine.
Volodymyr Borysovych Bogdanov+6 more
doaj
Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO+18 more
core +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Involvement of gap junction channels in the pathophysiology of migraine with aura
Migraine is a common, recurrent and disabling primary headache disorder with a genetic component which affects up to 20 % of the population. One third of all patients with migraine experiences aura, a focal neurological disturbance that manifests itself ...
Denis eSarrouilhe+2 more
doaj +1 more source
Effects of cortical spreading depression and ether following one-trial discriminated avoidance learning [PDF]
Manuel Black+2 more
openalex +1 more source
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Interhemispheric spread and graded response in spreading cortical depression [PDF]
Dianne A. Cofoid
openalex +1 more source
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian+17 more
wiley +1 more source
Spreading cortical depression blockage of seizures produced by electroconvulsive shock [PDF]
Richard W. Thompson, Joel Miller
openalex +1 more source