Results 191 to 200 of about 10,427 (246)

Safety and efficacy of intermittent fasting with or without exercise in people living with overweight or obesity and type 2 diabetes—The INTERFAST‐3 study design

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Aims Lifestyle modification, including caloric restriction and exercise, is fundamental in the treatment of people living with overweight and type 2 diabetes mellitus (T2D). The overall aim of lifestyle intervention schemes is to reduce body weight and improve glycaemic control to reduce the future risk of diabetes‐associated complications ...
Caren Sourij, Alexander Müller, Abdullah Al‐Baghdadi, Faisal Aziz, Norbert J. Tripolt, Peter N. Pferschy, Eva Andritz, Harald Kojzar, Vanessa Stadlbauer, Sabrina Leal Garcia, Harald Sourij   +10 more
wiley   +1 more source

Advancing Flexible Pressure Sensors for Next‐Generation Medical Monitoring

Advanced Sensor Research, Volume 5, Issue 6, June 2026.
This review highlights recent advances in flexible pressure sensors for next‐generation medical monitoring. The sensing mechanisms, material and structural optimization strategies, and intelligent algorithms are systematically summarized. Emerging applications in cardiovascular, respiratory, neurological, laryngeal, and ocular disease monitoring are ...
Chunjun Su, Xingfa Gao, Rixuan Wang, Shuhua Yang, Yinglun Sun   +4 more
wiley   +1 more source

A lifespan staging model of basal forebrain cholinergic vulnerability

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The cholinergic neurons of the basal forebrain are among the most vulnerable cell types to age‐ and Alzheimer's disease‐related dysfunction and neurodegeneration. However, the biological bases of basal forebrain cholinergic vulnerability (the why) and the temporal sequence (the how) have yet to be fully resolved.
Hayley R. C. Shanks, Sherry Chen, Kate M. Onuska, Taylor W. Schmitz   +3 more
wiley   +1 more source

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Cortical Spreading Depression and Migraine

Current Neurology and Neuroscience Reports, 2010
Cortical spreading depression, a slowly propagating wave of transient neuronal and glial depolarization, is widely accepted as the electrophysiologic substrate of migraine aura and a trigger for headache. Recent clinical and experimental evidence reinforces the putative role of cortical spreading depression in migraine pathophysiology.
Katharina Eikermann-Haerter, Cenk Ayata, Ayata Cenk   +2 more
exaly   +3 more sources

Cortical Spreading Depression in Migraine

Cephalalgia, 2001
Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that CSD is involved in the mechanism of migraine. This paper will, based on the experience related
Martin Lauritzen
exaly   +4 more sources

Cortical Spreading Depression in Rats

IEEE Engineering in Medicine and Biology Magazine, 2008
Cortical spreading depression (CSD) is an important neurophysiological phenomenon, which was first discovered more than 60 years ago. Optical intrinsic signal imaging (OISI) is a neuroimaging technique that can monitor a large region of the cortex with both higher temporal and spatial resolution.
Shangbin, Chen, Pengcheng, Li, Hui, Gong, Weihua, Luo, Shaoqun, Zeng, Qingming, Luo   +5 more
openaire   +2 more sources

Cortical Spreading Depression and Estrogen

Headache: The Journal of Head and Face Pain, 2007
Cortical spreading depression (CSD) is an electrophysiological phenomenon characterized by a wave of excitation followed by inhibition. The aura phase that precedes migraine headache in about 20‐30% of migraineurs shares overlapping characteristics with CSD. Studies of rare autosomal‐dominant forms of migraine with aura provide strong evidence that the
Katharina, Eikermann-Haerter, Chiho, Kudo, Michael A, Moskowitz   +2 more
openaire   +2 more sources

Cortical spreading depression and migraine

Nature Reviews Neurology, 2013
Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed by suppression of brain activity, is a remarkably complex event that involves dramatic changes in neural and vascular function. Since its original description in the 1940s, CSD has been hypothesized to be the underlying mechanism of the migraine aura.
Andrew C, Charles, Serapio M, Baca
openaire   +2 more sources

Cortical spreading depression: culprits and mechanisms

Experimental Brain Research, 2022
Cortical spreading depression or CSD is an electrophysiological phenomenon affecting various perspectives of brain physiology such as ionic balance, neurotransmitter level, and blood flow in the brain. This phenomenon has greater impact on the brain function and results in the pathological contribution of many diseases in humans such as migraine with ...
Aparna Ann, Mathew, Rajitha, Panonnummal
openaire   +2 more sources

Measurement of cortical pH in spreading cortical depression

American Journal of Physiology-Legacy Content, 1964
The pH of the rabbit cortex was measured during the course of spreading cortical depression. Spreading cortical depression was elicited by chemical (group I) and by electrical (group II) means. Cortical d-c potential changes were recorded separately by a glass membrane pH electrode and by a pore electrode.
S I, RAPOPORT, W H, MARSHALL
openaire   +2 more sources