Results 201 to 210 of about 1,302,249 (240)

Artificial Intelligence in Psychiatry: Five Decades of Progress and Persistent Translational Challenges

Psychiatric Research and Clinical Practice, EarlyView.
Objective This review examined the historical development of artificial intelligence (AI) in psychiatry from 1972 to 2025 and identified persistent barriers to clinical translation. Method The review used a structured source‐identification approach across PubMed/MEDLINE, Web of Science, Google Scholar, ScienceDirect, citation tracking, and targeted ...
Esteban Zavaleta‐Monestel, Luis Guillermo Herrera‐Jiménez, Sofía Suárez‐Sánchez, Sebastián Arguedas‐Chacón, Jeaustin Mora‐Jiménez, Ricardo Millán‐González   +5 more
wiley   +1 more source

Respiratory Support With Nasal High Flow Reduces Opioid Requirements During Endoscopic Retrograde Cholangiopancreatography

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Nasal high flow (NHF) improves oxygenation, reduces the work of breathing, and stabilizes ventilation. In endoscopic retrograde cholangiopancreatography (ERCP) under dexmedetomidine‐based sedation, opioids are often required but increase the risk of respiratory depression and delayed recovery.
Tomotaka Mori, Takao Ayuse, Shuntaro Sato, Taiga Ichinomiya, Rintaro Yano, Akane Shimakura, Yasuhiko Nakao, Kosuke Takahashi, Masanori Fukushima, Masafumi Haraguchi, Ryu Sasaki, Eisuke Ozawa, Satoshi Miuma, Stanislav Tatkov, Tetsuya Hara, Hisamitsu Miyaaki   +15 more
wiley   +1 more source

Persisting Region‐Specific Microglia Activation and Synaptic Imbalance During Remission in a DSS‐Induced Colitis Model

Glia, Volume 74, Issue 11, November 2026.
Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton, Luis E. Villafuerte, Alejandra P. Garza, Nina Lindemann, Elisa Wider‐Eberspächer, Dunja Bruder, Ildiko R. Dunay   +6 more
wiley   +1 more source

Cortical Spreading Depression Denotes Concussion Injury. [PDF]

J Neurotrauma, 2019
Bouley J, Chung DY, Ayata C, Brown RH, Henninger N.   +4 more
europepmc   +1 more source

Gq Signaling in Microglia Triggers Interferon Responses and Improves Outcome After Ischemic Stroke

Glia, Volume 74, Issue 10, October 2026.
Chemogenetic activation of Gq signaling in microglia ahead of ischemic stroke reduces infarct size in mice. Seven days after stroke, Gq‐primed microglia in the penumbra show enhanced interferon responses, altered branching patterns, and reduced phagocytosis.
Lynn Bitar, Marie‐Luise Brehme, Charlotte Oldenburg, Sara Isla Cainzos, Michael G. Kaul, Tobias Mummert, Malte Borggrewe, Thomas G. Oertner, Tim Magnus   +8 more
wiley   +1 more source

Psychological Adaptation During Prolonged War‐Related Stress in Ukraine: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Civilian populations exposed to prolonged stress, loss, illness, displacement, and other uncontrollable life events demonstrate substantial variability in psychological adaptation. Contemporary research suggests that psychological outcomes are influenced not only by the severity of adversity but also by patterns of ...
Nataliya Nekrasova, Yevgenia Solovyova, Dmytro Butov, Olivier Uwishema, Oksana Kauk   +4 more
wiley   +1 more source

Aquaporin-4-independent volume dynamics of astroglial endfeet during cortical spreading depression. [PDF]

Glia, 2019
Rosic B, Dukefoss DB, Åbjørsbråten KS, Tang W, Jensen V, Ottersen OP, Enger R, Nagelhus EA.   +7 more
europepmc   +1 more source

Microplastics as Emerging Neurotoxins: Brain Accumulation, Neuroinflammation, and Neurodegeneration Risk

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Microplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Alfi Sophian, Asmariani, Erika Ismayani
wiley   +1 more source

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang, Peng Cheng, Guangdong Liu, Yang Xiang, Zhen Hong, Weidong Le   +5 more
wiley   +1 more source

A computational study on the role of glutamate and NMDA receptors on cortical spreading depression using a multidomain electrodiffusion model. [PDF]

PLoS Comput Biol, 2019
Tuttle A, Riera Diaz J, Mori Y.
europepmc   +1 more source