Results 201 to 210 of about 30,052 (310)

Conceptualizing age‐appropriate social media to support children's digital futures

open access: yesBritish Journal of Developmental Psychology, EarlyView.
Abstract Is there really a ‘right age’ for social media? As governments rush to regulate children's digital lives, age‐based bans and ‘age‐appropriate’ design regulations are gaining international momentum. However, these are often based on theoretically dated ‘ages and stages’ models and blunt age thresholds.
Sonia Livingstone, Kim R. Sylwander
wiley   +1 more source

Shoreline and deglaciation chronology in southeast Norway

open access: yesBoreas, EarlyView.
The postglacial relative sea level history is reconstructed in four areas of mid‐ and inner Oslofjorden in southeast Norway. The reconstructions are based on radiocarbon‐dated raised shoreline levels from 42 sites, mainly isolation basins, and limiting ages from four lakes above the marine limit.
Anders Romundset   +6 more
wiley   +1 more source

Frontotemporal dementia: Clinical aspects, genetics, and neuropathology of a family with a C9ORF72 expansion in Argentina

open access: yesBrain Pathology, EarlyView.
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román   +13 more
wiley   +1 more source

Correction: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU‑005 reduces ex vivo cortical spreading depression. [PDF]

open access: yesJ Headache Pain
Brugia F   +8 more
europepmc   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito   +6 more
wiley   +1 more source

A Cacna1a Knockin Migraine Mouse Model with Increased Susceptibility to Cortical Spreading Depression [PDF]

open access: bronze, 2004
Arn M. J. M. van den Maagdenberg   +11 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

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