Results 61 to 70 of about 1,266,044 (253)

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Cortical thickness abnormalities in long-term remitted cushing’s disease

European Psychiatry, 2021
Introduction Remitted Cushing’s disease (RCD)-patients commonly continue to present persistent psychological and cognitive deficits, and alterations in brain function and structure.
S. Bauduin, Z. Van Der Pal, A. Pereira, O. Meijer, E. Giltay, N. Van Der Wee, S. Van Der Werff   +6 more
doaj   +1 more source

Grey matter abnormalities in social anxiety disorder: A pilot study

, 2012
ArticleWhile a number of studies have explored the functional neuroanatomy of social anxiety disorder (SAD), data on grey matter integrity are lacking. We conducted structural MRI scans to examine the cortical thickness of grey matter in individuals with
Hattingh C.J., Spottiswoode B., Syal S., Carey P.D., Lochner C., Stein D.J., Fouche J.-P.   +6 more
core   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Relationship between cortical thickness and serotonin 1A receptor binding in bipolar disorder

Translational Psychiatry
Deficits in cortical thickness have been a replicated finding in BD. Greater brain serotonin 1 A receptor (5HT1AR) binding has also been reported in BD, consistent with a disruption in serotonin signaling.
Martin J. Lan, Elizabeth Bartlett, Michael F. Schmidt, Maria A. Oquendo, Francesca Zanderigo, R. Todd Ogden, J. John Mann   +6 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Correlation Between Brain Structure Atrophy and Plasma Amyloid-β and Phosphorylated Tau in Patients With Alzheimer’s Disease and Amnestic Mild Cognitive Impairment Explored by Surface-Based Morphometry

Frontiers in Aging Neuroscience, 2022
ObjectiveTo investigate the changes in the cortical thickness of the region of interest (ROI) and plasma Aβ40, Aβ42, and phosphorylated Tau (P-Tau) concentrations in patients with Alzheimer’s disease (AD) and amnestic mild cognitive impairment (aMCI) as ...
Kaidi Li, Hang Qu, Mingyi Ma, Chenyu Xia, Ming Cai, Fang Han, Qing Zhang, Xinyi Gu, Qiang Ma   +8 more
doaj   +1 more source

The cortical signature of amyotrophic lateral sclerosis.

PLoS ONE, 2012
The aim of this study was to explore the pattern of regional cortical thickness in patients with non-familial amyotrophic lateral sclerosis (ALS) and to investigate whether cortical thinning is associated with disease progression rate. Cortical thickness
Federica Agosta, Paola Valsasina, Nilo Riva, Massimiliano Copetti, Maria Josè Messina, Alessandro Prelle, Giancarlo Comi, Massimo Filippi   +7 more
doaj   +1 more source

Thinner femoral cortical thickness in patients with destructive rheumatoid arthritis of the knee

Journal of Orthopaedic Surgery and Research, 2023
Background The examination of femoral cortical bone thickness in patients with rheumatoid arthritis (RA) has been notably limited in prior research. We aimed to compare femoral cortical thickness in patients with rheumatoid arthritis (RA) and healthy ...
Rika Kakutani, Naoki Kondo, Go Yamako, Tomoharu Mochizuki, Keiichiro Someya, Hiroyuki Kawashima   +5 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source