Results 41 to 50 of about 1,266,044 (253)

The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

, 2015
BACKGROUND. The disrupted in schizophrenia 1 (DISC1) gene locus was originally identified in a Scottish pedigree with a high incidence of psychiatric disorders that is associated with a balanced t(1;11)(q42.1;q14.3) chromosomal translocation.
Stefansson, H., Bois, C., Williams, S.C.R., Whitcher, B., Thomson, P., Turkheimer, F.E., Doyle, O.M., Romaniuk, L., McIntosh, A.M., Lawrie, S.M., Mehta, M.A.   +10 more
core   +1 more source

Assessing Intracortical Myelin in the Living Human Brain Using Myelinated Cortical Thickness

Frontiers in Neuroscience, 2015
Alterations in the myelination of the cerebral cortex may underlie abnormal cortical function in a variety of brain diseases. Here, we describe a technique for investigating changes in intracortical myelin in clinical populations on the basis of ...
Christopher Dennis Rowley, Pierre-Louis eBazin, Christine Lucas Tardif, Manpreet eSehmbi, Eyesha eHashim, Nadejda eZaharieva, Benicio eFrey, Lucianno eMinuzzi, Nicholas Adam Bock   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Regional cortical thinning in young adults with schizophrenia but not psychotic or non-psychotic bipolar I disorder

International Journal of Bipolar Disorders, 2018
Background Schizophrenia shares some genetic risk and clinical symptoms with bipolar disorder. Clinical heterogeneity across subjects is thought to contribute to variable structural imaging findings across studies. The current study investigates cortical
Douglass Godwin, Kathryn I. Alpert, Lei Wang, Daniel Mamah   +3 more
doaj   +1 more source

Altered cortical thickness and emotional dysregulation in adolescents with borderline personality disorder

European Journal of Psychotraumatology, 2023
Background: Emotional dysregulation is a core feature of borderline personality disorder (BPD). Previous studies have reported that abnormal grey matter volume is associated with the limbic–cortical circuit and default mode network (DMN) in patients with
Qian Xiao, Yan Fu, Xiaoping Yi, Jun Ding, Zaide Han, Zhejia Zhang, Zeming Tan, Jing Wang, Zijun Wu, Jingying Pi, Bihong T. Chen   +10 more
doaj   +1 more source

Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data.

, 2012
Patterns of brain atrophy measured by magnetic resonance structural imaging have been utilized as significant biomarkers for diagnosis of Alzheimer's disease (AD).
Jeong, Y., Alzheimer's Disease Neuroimaging Initiative, Whitcher, B., Seong, J.K., Cho, Y., Shin, S.Y.   +5 more
core   +1 more source

Direct cortical thickness estimation using deep learning‐based anatomy segmentation and cortex parcellation

, 2020
Accurate and reliable measures of cortical thickness from magnetic resonance imaging are an important biomarker to study neurodegenerative and neurological disorders.
Mauricio Reyes, Reyes, Mauricio, Wiest, Roland, McKinley, Richard, Michael Rebsamen, Christian Rummel, Richard McKinley, Rebsamen, Michael, Rummel, Christian, Roland Wiest   +9 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

GAMBARAN KETEBALAN DAN DENSITAS TULANG KORTIKAL MAKSILA DAN MANDIBULA MANUSIA PAWON DENGAN PENCITRAAN CONE BEAM COMPUTED TOMOGRAPHY 3D

Pubawidya: Jurnal Penelitian dan Pengembangan Arkeologi, 2017
The science on the existence of maxillary and mandibular cortical bone thickness and density of prehistoric human which had been found from Pawon cave, are  still uniden- tified by any research, further more if it is compared with those of modern human ...
Wisam Rizqullah, Azhari Azhari, Lusi Epsilawati, Lutfi Yondri, Fahmi Oscandar, Yuti Malinda   +5 more
doaj   +1 more source

Cortical thickness abnormalities in late adolescence with online gaming addiction. [PDF]

PLoS ONE, 2013
Online gaming addiction, as the most popular subtype of Internet addiction, had gained more and more attention from the whole world. However, the structural differences in cortical thickness of the brain between adolescents with online gaming addiction ...
Kai Yuan, Ping Cheng, Tao Dong, Yanzhi Bi, Lihong Xing, Dahua Yu, Limei Zhao, Minghao Dong, Karen M von Deneen, Yijun Liu, Wei Qin, Jie Tian   +11 more
doaj   +1 more source