Results 191 to 200 of about 95,041 (240)

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Electric Cataract After High-Voltage Craniofacial Injury With Preserved Optic Nerve Microvasculature: A Case Report. [PDF]

Clin Case Rep
Iqbal MI, Osman F.
europepmc   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Persistent auditory hallucinations despite hearing aid use in bilateral sensorineural hearing loss without evidence of psychosis. [PDF]

SAGE Open Med Case Rep
Elhusein B, Willis N, Ahmed S, De Tubino Scanavino M.   +3 more
europepmc   +1 more source

Visual Impairment and Driving in Older Adults: A Narrative Review. [PDF]

Curr Treat Options Neurol
Xu S, Ehrlich JR, De Lott LB.
europepmc   +1 more source

Posterior Atrophy is a Neuroimaging Marker of Mild Cognitive Impairment in Parkinson's Disease. [PDF]

Noro Psikiyatr Ars
Ay U, Yıldırım Z, Kicik A, Erdogdu E, Bilgiç B, Hanagasi H, Ozturk-Isık E, Demiralp T, Gurvit H.   +8 more
europepmc   +1 more source

Unveiling the cognitive fog in lung cancer patients: non-invasive exploration of blood-brain barrier disruption and brain structural changes. [PDF]

Ann Med
Zhang DF, Ma H, Zhang ZP, Ai J, Cao WT, Li ZH.   +5 more
europepmc   +1 more source

Clinical, Neuroimaging and Video Electroencephalography Findings in Children With Congenital Zika Syndrome: An Analysis From a Neurorehabilitation Centre. [PDF]

Int J Dev Neurosci
Rodrigues ASR, Silva PYF, Rodrigues RP, Pinho KGFD, da Costa Penha S, Leite ÁJM.   +5 more
europepmc   +1 more source