Results 131 to 140 of about 486,272 (240)

The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System

Glia, Volume 74, Issue 11, November 2026.
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada, Hinako Saito, Riko Takahashi, Mio Fujisato, Yukina Hosoda, Binri Sasaki, Momona Yamada, Sakurako Abe, Chikako Hayashi, Akira Yoshimoto, Ryunosuke Ohkawa, Tomal Julian Matt, Florence M Bareyre, Stefan Berghoff, Mikael Simons, Nobuharu Suzuki   +15 more
wiley   +1 more source

Dizziness, Scanning Speech, and Transient Hyperreflexia as Atypical Initial Manifestations of Antiganglioside Q1b‐Negative Miller Fisher Syndrome: A Case Report and Literature Review

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
This first report of Miller‐Fisher syndrome with dizziness and scanning speech as initial symptoms also showed CNS signs including hyperreflexia, intention tremor, and Babinski sign. Despite the eventual development of classic features and a favorable treatment response, the patient tested negative for anti‐GQ1b antibodies, suggesting a broader ...
Wenjing Wu, Mengying Mao, Bin Xu, Liang'e Xu   +3 more
wiley   +1 more source

Intratumoral and Peritumoral Functional Connectivity Reveals Network‐Level Signatures of Glioma

MedComm, Volume 7, Issue 11, November 2026.
Using resting‐state fMRI in 306 glioma patients, this study maps individualized intra‐ and peritumoral functional networks. Novel metrics (RIFR, RPTR) quantify tumor‐related network remodeling, correlating with pathology, structure, cognition, and survival. A prognostic model incorporating these network features achieves an AUC of 0.90.
Hongbo Bao, Yan Bai, Jie Hu, Wencai Ding, Jiacheng Lai, Andrew Zalesky, Ye Ella Tian, Yanmei Tie, Janet Mei, Shengyu Fang, Xing Fan, Licia P. Luna, Craig K. Jones, Jianxun Ren, Weigang Cui, Jiadong Yan, Zeya Yan, Zihan Wang, Renwu Zhang, Zhonghua Lv, Yihang Jiao, Tao Jiang, Peng Liang, Haris I. Sair, Yinyan Wang   +24 more
wiley   +1 more source

Transient effects in corticospinal and reticulospinal tract excitability induced by motor skill and isometric resistance training

Coordinated movement relies on the proper integration of multiple neural circuits. Motor training can alter the excitability of neural circuits controlling movement, but the pathway-specific effects to the lower limb of motor skill versus isometric ...
Seitz, Zachary, Keesey, Rodolfo, Se\ue1\uf1ez, Ismael, Hawthorn, Rachel, Atkinson, Carolyn, Nie, Haolin, Phelps, Natalie   +6 more
core   +1 more source

Somatotopic organization of the corticospinal tract in the human brainstem: A MRI-based mapping analysis

, 2005
To investigate the incompletely understood somatotopical organization of the corticospinal tract in the human brain-stem, we performed a voxel-based statistical analysis of standardized magnetic resonance scans of 41 prospectively recruited patients with
CRUCCU, Giorgio, Gian D. Iannetti, Peter P. Urban, Peter Stoeter, Marianne Dieterich, Frank Thomke, Hanns C. Hopf, Juergen J. Marx, Sabine Fitzek, Giorgio Cruccu   +9 more
core   +1 more source

The corticospinal tract from the viewpoint of brain rehabilitation

Journal of Rehabilitation Medicine, 2014
The corticospinal tract, a major neural tract in the human brain for motor function, is concerned mainly with movement of the distal extremities. Preservation or recovery of the corticospinal tract is essential for good recovery of impaired motor function in patients with brain injury.
openaire   +3 more sources

PTEN deletion facilitates corticospinal tract regeneration after chronic spinal cord injury

, 2013
Lack of regeneration of mature mammalian CNS leads to permanent functional loss after spinal cord injury. Studies show that neonatal PTEN deletion facilitates axon regeneration in corticospinal tract; however no treatment after chronic injury has shown ...
Du, Kaimeng
core  

Natural history and prognostic value of corticospinal tract Wallerian degeneration in intracerebral hemorrhage.

, 2013
The purpose of this study was to define the incidence, imaging characteristics, natural history, and prognostic implication of corticospinal tract Wallerian degeneration (CST-WD) in spontaneous intracerebral hemorrhage (ICH) using serial MR imaging ...
Gean, AD, Wijman, CAC, Fischbein, NJ, Gean-Gersch, Alisa, Snider, RW, Venkatasubramanian, C, Olivot, J-M, Mlynash, M, Kleinman, JT, Eyngorn, I   +9 more
core  

Targeted-Plasticity in the Corticospinal Tract After Human Spinal Cord Injury

, 2018
Spinal cord injury (SCI) often results in impaired or absent sensorimotor function below the level of the lesion. Recent electrophysiological studies in humans with chronic incomplete SCI demonstrate that voluntary motor output can be to some extent ...
Christiansen, Lasse, Perez, Monica A
core   +1 more source

A 12-week in-phase bilateral upper limb exercise protocol promoted neuroplastic and clinical changes in people with relapsing remitting multiple sclerosis: A registered report randomized single-case concurrent multiple baseline study.

PLoS ONE
IntroductionRelapsing-Remitting Multiple Sclerosis manifests various motor symptoms including impairments in corticospinal tract integrity, whose symptoms can be assessed using transcranial magnetic stimulation.
Dimitris Sokratous, Charalambos Costa Charalambous, Eleni Zamba-Papanicolaou, Kyriaki Michailidou, Nikos Konstantinou   +4 more
doaj   +1 more source