Results 41 to 50 of about 957,864 (297)

Transcranial Magnetic Stimulation Measures, Pyramidal Score on Expanded Disability Status Scale and Magnetic Resonance Imaging of Corticospinal Tract in Multiple Sclerosis

Bioengineering, 2023
Probing the cortic ospinal tract integrity by transcranial magnetic stimulation (TMS) could help to understand the neurophysiological correlations of multiple sclerosis (MS) symptoms. Therefore, the study objective was, first, to investigate TMS measures
Maja Rogić Vidaković, Ana Ćurković Katić, Sanda Pavelin, Antonia Bralić, Una Mikac, Joško Šoda, Ana Jerković, Angela Mastelić, Krešimir Dolić, Anita Markotić, Zoran Đogaš, Nikolina Režić Mužinić   +11 more
doaj   +1 more source

Does stroke location predict walk speed response to gait rehabilitation? [PDF]

, 2016
Objectives Recovery of independent ambulation after stroke is a major goal. However, which rehabilitation regimen best benefits each individual is unknown and decisions are currently made on a subjective basis.
Baron, Jean-Claude, Chandler, Elizabeth, Geva, Sharon, Jones, P. Simon, Kerr, Andrew, Marrapu, Siva, Pomeroy, Valerie, Rowe, Philip, Schlaug, Gottfried, Wang, Jasmine   +9 more
core   +1 more source

Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons

BMC Neuroscience, 2006
Background Inflammation around cell bodies of primary sensory neurons and retinal ganglion cells enhances expression of neuronal growth-associated genes and stimulates axonal regeneration.
Lieberman AR, Mason MRJ, MacNally JK, Rezajooi K, Hossain-Ibrahim MK, Anderson PN   +5 more
doaj   +1 more source

Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke

iScience, 2023
Summary: The limited intrinsic regrowth capacity of corticospinal axons impedes functional recovery after cortical stroke. Although the mammalian target of rapamycin (mTOR) and p53 pathways have been identified as the key intrinsic pathways regulating ...
Shuang Jin, Xiangfeng Chen, Hanyu Zheng, Wanxiong Cai, Xurong Lin, Xiangxing Kong, Yingchun Ni, Jingjia Ye, Xiaodan Li, Luoan Shen, Binjie Guo, Zeinab Abdelrahman, Songlin Zhou, Susu Mao, Yaxian Wang, Chun Yao, Xiaosong Gu, Bin Yu, Zhiping Wang, Xuhua Wang   +19 more
doaj   +1 more source

Longitudinal Optogenetic Motor Mapping Revealed Structural and Functional Impairments and Enhanced Corticorubral Projection after Contusive Spinal Cord Injury in Mice [PDF]

, 2019
Current evaluation of impairment and repair after spinal cord injury (SCI) is largely dependent on behavioral assessment and histological analysis of injured tissue and pathways. Here, we evaluated whether transcranial optogenetic mapping of motor cortex
Chai, Zhi, Jin, Xiaoming, Qian, Jun, Wu, Wei, Xiong, Wenhui, Xu, Xiao-Ming   +5 more
core   +1 more source

Maturation of Corticospinal Tracts in Children With Hemiplegic Cerebral Palsy Assessed by Diffusion Tensor Imaging and Transcranial Magnetic Stimulation

Frontiers in Human Neuroscience, 2019
Aim: To assess changes in the developmental trajectory of corticospinal tracts (CST) maturation in children with hemiplegic cerebral palsy (HCP).Methods: Neuroimaging data were obtained from 36 children with HCP for both the more affected (MA) and less ...
Christos Papadelis, Christos Papadelis, Harper Kaye, Harper Kaye, Benjamin Shore, Brian Snyder, Patricia Ellen Grant, Patricia Ellen Grant, Alexander Rotenberg, Alexander Rotenberg, Alexander Rotenberg   +10 more
doaj   +1 more source

Chimpanzee (Pan troglodytes) precentral corticospinal system asymmetry and handedness: a diffusion magnetic resonance imaging study. [PDF]

PLoS ONE, 2010
Most humans are right handed, and most humans exhibit left-right asymmetries of the precentral corticospinal system. Recent studies indicate that chimpanzees also show a population-level right-handed bias, although it is less strong than in humans.We ...
Longchuan Li, Todd M Preuss, James K Rilling, William D Hopkins, Matthew F Glasser, Bhargav Kumar, Roger Nana, Xiaodong Zhang, Xiaoping Hu   +8 more
doaj   +1 more source

Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]

, 2019
Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin, Dobkins, Gabriel, Ferguson, Adam R, Gomes-Leal, Walace, Graham, Lori, Huie, J Russell, Lu, Paul, Tuszynski, Mark   +7 more
core   +1 more source

Neurite orientation and dispersion density imaging (NODDI) detects cortical and corticospinal tract degeneration in ALS

Journal of Neurology Neurosurgery & Psychiatry, 2018
Background Corticospinal tract (CST) degeneration and cortical atrophy are consistent features of amyotrophic lateral sclerosis (ALS). We hypothesised that neurite orientation dispersion and density imaging (NODDI), a multicompartment model of diffusion ...
R. Broad, M. Gabel, N. Dowell, D. Schwartzman, A. Seth, Hui Zhang, D. Alexander, M. Cercignani, P. Leigh   +8 more
semanticscholar   +1 more source

Occasional essay: upper motor neuron syndrome in amyotrophic lateral sclerosis [PDF]

, 2020
The diagnosis of amyotrophic lateral sclerosis (ALS) requires recognition of both lower (LMN) and upper motor neuron (UMN) dysfunction.1 However, classical UMN signs are frequently difficult to identify in ALS.2 LMN involvement is sensitively detected ...
Burke, David, deCarvalho, Mamede, Grosskreutz, Julian, Kiernan, Matthew C, Leigh, P Nigel, Swash, Michael, Turner, Martin R   +6 more
core   +1 more source