Results 51 to 60 of about 486,272 (240)

Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice

open access: yesNeural Regeneration Research
Stroke can cause Wallerian degeneration in regions outside of the brain, particularly in the corticospinal tract. To investigate the fate of major glial cells and axons within affected areas of the corticospinal tract following stroke, we induced ...
Jiao Mu   +8 more
doaj   +1 more source

The Cortical “Upper Motoneuron” in Health and Disease

open access: yesBrain Sciences, 2021
Upper motoneurons (UMNs) in motor areas of the cerebral cortex influence spinal and cranial motor mechanisms through the corticospinal tract (CST) and through projections to brainstem motor pathways.
Roger N. Lemon
doaj   +1 more source

Exploration the changes in white matter fiber bundles and their relationship with the degree of neurological dysfunction in patients with ischemic stroke

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the changes in white matter fiber bundles in patients with ischemic stroke after endovascular treatment and their correlation with the degree of neurological dysfunction.
WANG Bin, MA Fu-kun, REN Yi
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Motor pathway degeneration in young ataxia telangiectasia patients: A diffusion tractography study

open access: yesNeuroImage: Clinical, 2015
Background: Our understanding of the effect of ataxia–telangiectasia mutated gene mutations on brain structure and function is limited. In this study, white matter motor pathway integrity was investigated in ataxia telangiectasia patients using diffusion
Ishani Sahama   +7 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse   +13 more
wiley   +1 more source

Frequency and Phenotype of Coexisting Aquaporin‐4 and Autoimmune Encephalitis Autoantibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Among 9457 aquaporin‐4 (AQP4) immunoglobulin G‐positive patients, 2071 underwent autoimmune encephalitis antibody testing and 85 (4%) had coexisting antibodies, most commonly cerebrospinal fluid glial fibrillary acidic protein‐IgG and N‐methyl‐D‐aspartate receptor‐IgG, or serum high‐titer GAD65‐IgG.
Laura Cacciaguerra   +25 more
wiley   +1 more source

Teaching Neuro Image :Corticospinal tract [PDF]

open access: yesNeurology, 2008
A 60-year-old man presented with progressive weakness for 2 years that began in the right arm and subsequently spread to all limbs. On examination, he had both upper and lower motor …
Sheng-Han, Kuo, Justin Y, Kwan
openaire   +2 more sources

Functional connectivity and upper limb function in patients after pediatric arterial ischemic stroke with contralateral corticospinal tract wiring. [PDF]

open access: yes, 2021
To develop individualized motor rehabilitation, knowledge of the relationship between neuroplastic reorganization and motor recovery after pediatric arterial ischemic stroke (AIS) is crucial.
Everts, Regula   +23 more
core   +2 more sources

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