Results 141 to 150 of about 340,216 (249)

Systemic Corticosteroid as an Adjunct for Acute Respiratory Distress Syndrome in Non-Fatal Fresh Water Drowning: An Evidence-based Case Report

open access: yesActa Medica Indonesiana
Background: Acute lung injury or acute respiratory distress syndrome (ARDS) is one of the most common complications of non-fatal drowning. Although respiratory societies’ guidelines endorse the role of systemic corticosteroids in ARDS, the evidence for ...
Eric Daniel Tenda   +7 more
doaj  

Safe Use of Corticosteroids in Non-Infectious Uveitis. [PDF]

open access: yesJ Inflamm Res
Belletti M   +5 more
europepmc   +1 more source

Medication adherence during the run‐in phase of clinical trials: A systematic review of methodological and reporting rigour

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Trial run‐in phases are sometimes used to select adherent participants as a strategy to enrich trials, but the methods employed lack clear regulatory guidance and there are concerns about the transparency of reporting. This review aims to characterize the methods used for adherence measurement and public reporting of run‐in studies.
Non Davies   +3 more
wiley   +1 more source

Mild psoriasis as a suitable model for proof‐of‐mechanism in a phase 1B setting: Results from a double‐blind placebo‐controlled trial with guselkumab

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Early clinical development of novel psoriasis therapies is hampered by a decreasing number of moderate‐to‐severe psoriasis patients eligible for participation in trials since efficacious treatments, such as biologics, have become widely available.
Jannik Rousel   +11 more
wiley   +1 more source

Development of Sarcoidosis Subsequent to Temporary Corticosteroid Treatment in a Patient With Rheumatoid Arthritis. [PDF]

open access: yesRespirol Case Rep
Itami T   +11 more
europepmc   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl   +11 more
wiley   +1 more source

Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium

open access: yesHepatology Communications, EarlyView., 2022
Abstract Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retrospective cohort study of adult SLKT recipients between 2002 and 2017 at six centers in six United Network ...
Jennifer Jo   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy