The effects of β2‐adrenoceptor agonists and a corticosteroid, budesonide, on the secretion of inflammatory mediators from monocytes [PDF]
Margareta Linden
openalex +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk +6 more
wiley +1 more source
Identification of Novel Biomarkers Associated with Corticosteroid Resistance in Asthma by Bioinformatics Analysis and Experimental Validation. [PDF]
Xuan L, Ren L, Zhang W, An Z.
europepmc +1 more source
Sarcoidosis revealed by recurrent dactylitis.
Arthritis &Rheumatology, Accepted Article.
Thomas Subervie +7 more
wiley +1 more source
Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas +7 more
wiley +1 more source
Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation. [PDF]
Ruyuan L +3 more
europepmc +1 more source
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård +6 more
wiley +1 more source
Cortisol Testing in Septic Shock: An Evaluation of Diagnostic Performance and Predictors of Corticosteroid Use in a Middle Eastern Cohort. [PDF]
Alshamsi F +5 more
europepmc +1 more source

