Results 161 to 170 of about 516,590 (413)

Risk factors for wound infection in surgery for spinal metastasis [PDF]

, 2015
Wound infection rates are generally higher in patients undergoing surgery for spinal metastasis. Risk factors of wound infection in these patients are poorly understood.
A Grzegorzewska, AF Pull ter Gunne, D. van Popta, H Majeed, H Pascal-Moussellard, I McPhee, I. Siddique, IA Omeis, J Wise, J. Stephenson, KA Greene, N Sarhill, R. R. Verma, R. Rodrigues-Pinto, S Boriani, S Demura, S Dickhaut, S. Kumar, S. Mohammad   +18 more
core   +1 more source

A case of patch granuloma annulare with CD68‐negative, CD163‐positive M2 macrophages infiltration in an interstitial pattern

Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 236-237, December 2022., 2022
Patch granuloma annulare is a rare type of granuloma annulare. Histopathologically, patch granuloma annulare shows interstitial infiltration of histiocytes. In our case, immunohistochemical analyses demonstrated CD68‐negative, CD163‐positive M2 macrophages infiltration in an interstitial pattern.
Kenta Ikeda, Kazuko Mizuno, Osamu Yamasaki, Shin Morizane   +3 more
wiley   +1 more source

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

The Lancet, 2020
Chen Wang, P. Horby, F. G. Hayden, G. Gao   +3 more
semanticscholar   +1 more source

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease.

Cochrane Database of Systematic Reviews, 2014
BACKGROUND Current guidelines recommend that patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) should be treated with systemic corticosteroid for seven to 14 days.
J. Walters, Daniel J Tan, Clinton J White, R. Wood‐Baker   +3 more
semanticscholar   +1 more source

Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial. [PDF]

, 2015
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity, mortality, and health-care costs. An incomplete response to the anti-inflammatory effects of inhaled corticosteroids is present in COPD.
Alyn Morice, Amanda J. Lee, Andrew Briggs, Andrew Wilson, Anita Sullivan, Anthony De Soyza, B Shah, BG Cosio, BG Cosio, BR Celli, CM Fletcher, David Price, E Stahl, G Cusack, GC Donaldson, GC Donaldson, Gladys McPherson, Graham Burns, Graham Devereux, H Chrystyn, H Chrystyn, H Chrystyn, H Chrystyn, Henry Chrystyn, JA Marwick, JC Bestall, JJ Soler-Cataluna, JK Quint, John Haughney, John Norrie, JR Hurst, JR Powell, JR Powell, JW Dodd, K Ito, K Ito, K Ito, K Ito, K Ohta, KC Farmer, Kirsty McCormack, KL Hattotuwa, L Hendeles, Lisa Davies, M Britton, M Ferrer, MC Cyr, MR Miller, P Dolan, P Sullivan, PA Ford, Peter Barnes, PJ Barnes, PJ Barnes, PW Jones, Rekha Chaudhuri, RG Barr, S Lim, Seonaidh Cotton, Shona Fielding, Simon Gompertz, SN Hunt, SV Culpitt, SV Culpitt, TA Seemungal, The EuroQol Group, WJ Jusko, WJ Jusko, Y To   +68 more
core   +4 more sources

Persistent Eosinophilic Inflammation Is Not a Feature of Type 2 CRS Patients Failing Anti‐IL‐5R Therapy and Requiring Class Switching to Anti‐IL‐4/13

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Type 2 inflammation dominates eosinophilic chronic rhinosinusitis (eCRS) and adult onset asthma. IL‐4, ‐5, and ‐13 are prominent disease mediators. Disease control can be achieved with biologic therapies. However, despite some patients entering remission, others experience poor control. Aim We aimed to describe eCRS patients treated
Peta‐Lee Sacks, Christian M Meerwein, Peter Earls, Cedric Thiel, Christine Choy, Raewyn G Campbell, Raymond Sacks, Larry Kalish, Richard J Harvey   +8 more
wiley   +1 more source

Immediate hypersensitivity reaction to carboxymethylcellulose in lidocaine jelly and dimethicone drops: A case report and mini‐review

Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 217-221, December 2022., 2022
Carboxymethylcellulose (CMC, carmellose sodium) is an anionic water‐soluble polymer derived from native cellulose that is used as an excipient. Here, we report a case of urticaria caused by the CMC in lidocaine jelly and dimethicone drops. Abstract Excipient allergies are rare and difficult to diagnose.
Eri Hotta, Risa Tamagawa‐Mineoka, Yuri Onishi, Ayaka Sotozono, Megumi Kusunoki, Junko Hattori, Natsue Ioka, Hiromi Mizutani, Koji Masuda, Norito Katoh   +9 more
wiley   +1 more source

Association of Asthma Diagnosis and Medication Use with Fecundability: A Prospective Cohort Study

Clinical Epidemiology, 2020
Holly Michelle Crowe,1 Lauren Anne Wise,1 Amelia Kent Wesselink,1 Kenneth Jay Rothman,1,2 Ellen Margrethe Mikkelsen,3 Henrik Toft Sørensen,3 Allan Jay Walkey,4 Elizabeth Elliott Hatch1 1Department of Epidemiology, Boston University School of ...
Crowe HM, Wise LA, Wesselink AK, Rothman KJ, Mikkelsen EM, Sørensen HT, Walkey AJ, Hatch EE   +7 more
doaj  

Comparison of Transcriptional Activation by Corticosteroids of Human MR (Ile-180) and Human MR Haplotype (Ile180Val) [PDF]

arXiv
While the classical function of human mineralocorticoid receptor (MR) is to regulate sodium and potassium homeostasis through aldosterone activation of the kidney MR, the MR also is highly expressed in the brain, where the MR is activated by cortisol in response to stress. Here, we report the half-maximal response (EC50) and fold-activation by cortisol,
arxiv  

Identification of structural features in chemicals associated with cancer drug response: A systematic data-driven analysis [PDF]

arXiv, 2013
Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug thera-pies. New methods are required for integrated analyses of a large number of chemical features of drugs against the corresponding genome-wide responses of
arxiv