Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz +3 more
wiley +1 more source
High-Dose Hormone Replacement Therapy Improved Embryo Transfer Outcomes in a Woman With 21-Hydroxylase Deficiency Who Had Persistently High Serum Progesterone Levels: A Case Report and Literature Review. [PDF]
Mizusawa Y, Shibahara H, Shiotani M.
europepmc +1 more source
This study explored a combined therapy of Brassica rapa L. polysaccharides and dexamethasone with an improved anti‐rheumatic and immunomodulatory effects, which also altered gut microbiome and gut barrier disruption in regulation of rheumatoid arthritis.
Hongkang Zhu +3 more
wiley +1 more source
Successful Immunotherapy Rechallenge Without Recurrence of Hemophagocytic Lymphohistiocytosis in a Patient With Metastatic Endometrial Cancer Previously Treated With Dostarlimab. [PDF]
Rollet E +4 more
europepmc +1 more source
Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects
Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid +3 more
wiley +1 more source
Age at disease onset is an independent risk factor for physical growth of children with idiopathic pulmonary hemosiderosis. [PDF]
Li S, Li T, Zhou L, Mou D, Sun M.
europepmc +1 more source
The protective effects of Medulla Tetrapanacis (MT) water extract on dextran sulfate sodium‐induced ulcerative colitis (UC) were examined both in vivo (mouse and zebrafish) and in vitro. The effect of MT on UC was mediated by regulating macrophage polarization, ameliorating oxidative stress, and preserving an intact intestinal barrier. The effect of MT
Yanfen Cheng +10 more
wiley +1 more source
Comparative plasma metabolomics of Delta and Omicron SARS-CoV-2 variants: insights into variant-specific pathogenesis and therapeutic implications. [PDF]
Pimentel E +3 more
europepmc +1 more source
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han +7 more
wiley +1 more source

